BAIT

FSHR

FSHRO, LGR1, ODG1
follicle stimulating hormone receptor
GO Process (7)
GO Function (1)
GO Component (1)

Gene Ontology Biological Process

Gene Ontology Molecular Function

Gene Ontology Cellular Component

Homo sapiens
PREY

APPL2

DIP13B
adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 2
GO Process (2)
GO Function (1)
GO Component (5)

Gene Ontology Biological Process

Gene Ontology Molecular Function

Gene Ontology Cellular Component

Homo sapiens

Affinity Capture-Western

An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner identified by Western blot with a specific polyclonal antibody or second epitope tag. This category is also used if an interacting protein is visualized directly by dye stain or radioactivity. Note that this differs from any co-purification experiment involving affinity capture in that the co-purification experiment involves at least one extra purification step to get rid of potential contaminating proteins.

Publication

APPL1, APPL2, Akt2 and FOXO1a interact with FSHR in a potential signaling complex.

Nechamen CA, Thomas RM, Dias JA

A number of signaling proteins have been demonstrated to interact with follicle stimulating hormone (FSH) receptor (FSHR), including APPL1, 14-3-3tau and Akt2. To further define the repertoire of proteins involved in FSH-induced signal transduction, several signaling and adapter proteins were examined for the ability to associate with FSHR. This report shows that, in addition to APPL1, FSHR interacts with FOXO1a ... [more]

Mol. Cell. Endocrinol. Jan. 02, 2007; 260(0);93-9 [Pubmed: 17030088]

Throughput

  • Low Throughput

Additional Notes

  • figure 1.

Curated By

  • BioGRID