PREY

RABGAP1

GAPCENA, TBC1D11, HSPC094
RAB GTPase activating protein 1
GO Process (3)
GO Function (4)
GO Component (3)
Homo sapiens

Phenotypic Suppression

A genetic interaction is inferred when mutation or over expression of one gene results in suppression of any phenotype (other than lethality/growth defect) associated with mutation or over expression of another gene.

Publication

Identification of the ligands of protein interaction domains through a functional approach.

Caratu G, Allegra D, Bimonte M, Schiattarella GG, D'Ambrosio C, Scaloni A, Napolitano M, Russo T, Zambrano N

The identification of protein-protein interaction networks has often given important information about the functions of specific proteins and on the cross-talk among metabolic and regulatory pathways. The availability of entire genome sequences has rendered feasible the systematic screening of collections of proteins, often of unknown function, aimed to find the cognate ligands. Once identified by genetic and/or biochemical approaches, the ... [more]

Mol. Cell Proteomics Feb. 01, 2007; 6(2);333-45 [Pubmed: 17124247]

Throughput

  • Low Throughput

Additional Notes

  • figure 7.

Curated By

  • BioGRID