BAIT

HABP4

IHABP-4, IHABP4, Ki-1/57, SERBP1L, RP11-172F4.4

hyaluronan binding protein 4

GO Process (5)

GO Function (1)

GO Component (6)

Gene Ontology Biological Process

blood coagulation [TAS]

cellular response to mechanical stimulus [ISS]

negative regulation of DNA binding [IDA]

platelet activation [TAS]

platelet degranulation [TAS]

Gene Ontology Molecular Function

protein binding [IPI]

Gene Ontology Cellular Component

cytoplasm [IDA, ISS]

extracellular region [TAS]

nucleoplasm [IDA]

sarcomere [ISS]

CRISPR Database VEGA HGNC Alliance of Genome Resources Entrez Gene RefSeq UniprotKB Ensembl HPRD

Homo sapiens

PREY

C1QBP

GC1QBP, HABP1, SF2p32, gC1Q-R, gC1qR, p32

complement component 1, q subcomponent binding protein

GO Process (21)

GO Function (9)

GO Component (7)

Gene Ontology Biological Process

blood coagulation [TAS]

blood coagulation, intrinsic pathway [TAS]

immune response [TAS]

mature ribosome assembly [IMP]

negative regulation of MDA-5 signaling pathway [IDA]

negative regulation of RIG-I signaling pathway [IDA]

negative regulation of defense response to virus [IMP]

negative regulation of interferon-gamma production [IDA]

negative regulation of interleukin-12 production [IDA]

negative regulation of mRNA splicing, via spliceosome [IDA]

negative regulation of transcription from RNA polymerase II promoter [IDA]

phosphatidylinositol 3-kinase signaling [IMP]

positive regulation of apoptotic process [IMP]

positive regulation of cell adhesion [IMP]

positive regulation of dendritic cell chemotaxis [IMP]

positive regulation of mitochondrial translation [ISS]

positive regulation of neutrophil chemotaxis [IDA]

positive regulation of protein kinase B signaling [IMP]

positive regulation of substrate adhesion-dependent cell spreading [IMP]

positive regulation of trophoblast cell migration [IMP]

regulation of complement activation [IDA]

Gene Ontology Molecular Function

adrenergic receptor binding [ISS]
complement component C1q binding [IDA]
hyaluronic acid binding [IDA]
kininogen binding [IDA]
mRNA binding [ISS]
mitochondrial ribosome binding [ISS]
protein binding [IPI]
transcription corepressor activity [IDA]
transcription factor binding [IDA]

Gene Ontology Cellular Component

cell surface [IDA]

cytoplasm [ISS]

mitochondrion [IDA]

plasma membrane [TAS]

CRISPR Database VEGA OMIM HGNC Alliance of Genome Resources Entrez Gene RefSeq UniprotKB Ensembl HPRD

Homo sapiens

Two-hybrid

Bait protein expressed as a DNA binding domain (DBD) fusion and prey expressed as a transcriptional activation domain (TAD) fusion and interaction measured by reporter gene activation.

Publication

Functional association of human Ki-1/57 with pre-mRNA splicing events.

Bressan GC, Quaresma AJ, Moraes EC, Manfiolli AO, Passos DO, Gomes MD, Kobarg J

The cytoplasmic and nuclear protein Ki-1/57 was first identified in malignant cells from Hodgkin's lymphoma. Despite studies showing its phosphorylation, arginine methylation, and interaction with several regulatory proteins, the functional role of Ki-1/57 in human cells remains to be determined. Here, we investigated the relationship of Ki-1/57 with RNA functions. Through immunoprecipitation assays, we verified the association of Ki-1/57 with ... [more]

FEBS J. Jul. 01, 2009; 276(14);3770-83 [Pubmed: 19523114]

Throughput

Low Throughput

Related interactions

Interaction	Experimental Evidence Code	Dataset	Throughput	Score	Curated By	Notes
HABP4 C1QBP	Two-hybrid Two-hybrid Bait protein expressed as a DNA binding domain (DBD) fusion and prey expressed as a transcriptional activation domain (TAD) fusion and interaction measured by reporter gene activation.	Nery FC (2006)	Low	-	BioGRID	-

Curated By

BioGRID