BAIT
PPP1R14A
CPI-17, CPI17, PPP1INL
protein phosphatase 1, regulatory (inhibitor) subunit 14A
GO Process (0)
GO Function (0)
GO Component (0)
Homo sapiens
PREY
CSNK1E
CKIepsilon, HCKIE, RP1-5O6.1
casein kinase 1, epsilon
GO Process (12)
GO Function (4)
GO Component (3)
Gene Ontology Biological Process
- DNA repair [TAS]
- G2/M transition of mitotic cell cycle [TAS]
- Wnt signaling pathway [IBA]
- circadian regulation of gene expression [ISS]
- endocytosis [IBA]
- mitotic cell cycle [TAS]
- peptidyl-serine phosphorylation [IBA]
- positive regulation of proteasomal ubiquitin-dependent protein catabolic process [ISS]
- protein phosphorylation [IDA, ISS]
- regulation of cell shape [IBA]
- regulation of circadian rhythm [ISS]
- signal transduction [TAS]
Gene Ontology Molecular Function
Homo sapiens
Reconstituted Complex
An interaction is detected between purified proteins in vitro.
Publication
Association of CPI-17 with protein kinase C and casein kinase I.
The protein kinase C-potentiated inhibitor protein of 17kDa, called CPI-17, specifically inhibits myosin light chain phosphatase (MLCP). Phosphorylation of Thr-38 in vivo highly potentiates the ability of CPI-17 to inhibit MLCP. Thr-38 has been shown to be phosphorylated in vitro by a number of protein kinases including protein kinase C (PKC), Rho-associated coiled-coil kinase (ROCK), and protein kinase N (PKN). ... [more]
Biochem. Biophys. Res. Commun. Mar. 26, 2004; 316(1);39-47 [Pubmed: 15003508]
Throughput
- Low Throughput
Curated By
- BioGRID