BAIT
APTX
AOA, AOA1, AXA1, EAOH, EOAHA, FHA-HIT, RP11-562M8.1
aprataxin
GO Process (8)
GO Function (10)
GO Component (5)
Gene Ontology Biological Process
Gene Ontology Molecular Function- DNA 5'-adenosine monophosphate hydrolase activity [IDA]
- chromatin binding [IDA]
- damaged DNA binding [IDA]
- double-stranded DNA binding [IDA]
- double-stranded RNA binding [IDA]
- phosphoglycolate phosphatase activity [IDA]
- phosphoprotein binding [IPI]
- polynucleotide 3'-phosphatase activity [IDA]
- protein N-terminus binding [IPI]
- protein binding [IPI]
- DNA 5'-adenosine monophosphate hydrolase activity [IDA]
- chromatin binding [IDA]
- damaged DNA binding [IDA]
- double-stranded DNA binding [IDA]
- double-stranded RNA binding [IDA]
- phosphoglycolate phosphatase activity [IDA]
- phosphoprotein binding [IPI]
- polynucleotide 3'-phosphatase activity [IDA]
- protein N-terminus binding [IPI]
- protein binding [IPI]
Gene Ontology Cellular Component
Homo sapiens
PREY
HSPA4
APG-2, HEL-S-5a, HS24/P52, HSPH2, RY, hsp70, hsp70RY
heat shock 70kDa protein 4
GO Process (3)
GO Function (1)
GO Component (3)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
Affinity Capture-MS
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.
Publication
A new XRCC1-containing complex and its role in cellular survival of methyl methanesulfonate treatment.
DNA single-strand break repair (SSBR) is important for maintaining genome stability and homeostasis. The current SSBR model derived from an in vitro-reconstituted reaction suggests that the SSBR complex mediated by X-ray repair cross-complementing protein 1 (XRCC1) is assembled sequentially at the site of damage. In this study, we provide biochemical data to demonstrate that two preformed XRCC1 protein complexes exist ... [more]
Mol. Cell. Biol. Oct. 01, 2004; 24(19);8356-65 [Pubmed: 15367657]
Throughput
- Low Throughput
Curated By
- BioGRID