EIF4A3
Gene Ontology Biological Process
- ATP catabolic process [IDA]
- RNA metabolic process [TAS]
- cytokine-mediated signaling pathway [TAS]
- embryonic cranial skeleton morphogenesis [IMP]
- gene expression [TAS]
- mRNA metabolic process [TAS]
- mRNA splicing, via spliceosome [IC]
- negative regulation of translation [IDA]
- nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay [TAS]
- nuclear-transcribed mRNA catabolic process, nonsense-mediated decay [IMP, TAS]
- nuclear-transcribed mRNA poly(A) tail shortening [TAS]
- positive regulation of translation [IMP]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
SNRPB
Gene Ontology Biological Process
- RNA metabolic process [TAS]
- RNA splicing [TAS]
- gene expression [TAS]
- histone mRNA metabolic process [TAS]
- mRNA 3'-end processing [TAS]
- mRNA splicing, via spliceosome [IC, TAS]
- ncRNA metabolic process [TAS]
- spliceosomal snRNP assembly [IDA, TAS]
- termination of RNA polymerase II transcription [TAS]
- transcription from RNA polymerase II promoter [TAS]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Affinity Capture-MS
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.
Publication
The cellular EJC interactome reveals higher-order mRNP structure and an EJC-SR protein nexus.
In addition to sculpting eukaryotic transcripts by removing introns, pre-mRNA splicing greatly impacts protein composition of the emerging mRNP. The exon junction complex (EJC), deposited upstream of exon-exon junctions after splicing, is a major constituent of spliced mRNPs. Here, we report comprehensive analysis of the endogenous human EJC protein and RNA interactomes. We confirm that the major "canonical" EJC occupancy ... [more]
Throughput
- High Throughput
Related interactions
Interaction | Experimental Evidence Code | Dataset | Throughput | Score | Curated By | Notes |
---|---|---|---|---|---|---|
SNRPB EIF4A3 | Affinity Capture-MS Affinity Capture-MS An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods. | High | - | BioGRID | 3370565 |
Curated By
- BioGRID