BAIT
OS9
ERLEC2, OS-9
osteosarcoma amplified 9, endoplasmic reticulum lectin
GO Process (5)
GO Function (2)
GO Component (2)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
PREY
PPIB
CYP-S1, CYPB, HEL-S-39, OI9, SCYLP
peptidylprolyl isomerase B (cyclophilin B)
GO Process (7)
GO Function (6)
GO Component (7)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
Affinity Capture-MS
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.
Publication
Unassembled CD147 is an endogenous endoplasmic reticulum-associated degradation substrate.
Degradation of folding- or assembly-defective proteins by the endoplasmic reticulum-associated degradation (ERAD) ubiquitin ligase, Hrd1, is facilitated by a process that involves recognition of demannosylated N-glycans by the lectin OS-9/XTP3-B via the adaptor protein SEL1L. Most of our knowledge of the machinery that commits proteins to this fate in metazoans comes from studies of overexpressed mutant proteins in heterologous cells. ... [more]
Mol. Biol. Cell Dec. 01, 2012; 23(24);4668-78 [Pubmed: 23097496]
Throughput
- Low Throughput
Curated By
- BioGRID