EDNRA
Gene Ontology Biological Process
- G-protein coupled receptor signaling pathway [TAS]
- Rho protein signal transduction [ISO]
- artery smooth muscle contraction [ISO]
- cellular response to mechanical stimulus [ISO]
- endothelin receptor signaling pathway [IMP, ISO]
- fibroblast proliferation [ISO]
- glomerular filtration [ISO]
- glucose transport [IDA]
- head development [IMP]
- heart development [IGI]
- histamine secretion [ISO]
- in utero embryonic development [IMP]
- negative regulation of apoptotic process [ISO]
- negative regulation of cAMP biosynthetic process [IGI]
- neural crest cell development [IMP]
- patterning of blood vessels [IGI]
- penile erection [ISO]
- positive regulation of ERK1 and ERK2 cascade [ISO]
- positive regulation of calcium ion transport [ISO]
- positive regulation of cell proliferation [ISO]
- positive regulation of cytosolic calcium ion concentration [ISO]
- positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G-protein coupled signaling pathway [ISO]
- positive regulation of inflammatory response [ISO]
- positive regulation of kidney development [ISO]
- positive regulation of neutrophil chemotaxis [ISO]
- positive regulation of odontogenesis [ISO]
- positive regulation of protein phosphorylation [ISO]
- positive regulation of release of sequestered calcium ion into cytosol [ISO]
- protein kinase C-activating G-protein coupled receptor signaling pathway [ISO]
- regulation of blood pressure [IMP]
- regulation of epithelial cell proliferation [ISO]
- respiratory gaseous exchange [IMP]
- response to hypoxia [IMP]
- response to lipopolysaccharide [ISO]
- response to morphine [ISO]
- sensory perception of pain [ISO]
- smooth muscle cell proliferation [ISO]
- vasoconstriction [IMP, ISO]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
YES1
Gene Ontology Biological Process
- cell differentiation [IBA]
- cellular response to peptide hormone stimulus [IBA]
- cellular response to platelet-derived growth factor stimulus [IDA]
- cellular response to retinoic acid [IDA]
- cellular response to transforming growth factor beta stimulus [IGI]
- glucose transport [IDA]
- innate immune response [IBA]
- peptidyl-tyrosine autophosphorylation [IBA]
- positive regulation of peptidyl-tyrosine phosphorylation [IDA]
- positive regulation of transcription from RNA polymerase II promoter [IGI]
- protein autophosphorylation [ISO]
- regulation of cell proliferation [IBA]
- transmembrane receptor protein tyrosine kinase signaling pathway [IBA]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Affinity Capture-Western
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner identified by Western blot with a specific polyclonal antibody or second epitope tag. This category is also used if an interacting protein is visualized directly by dye stain or radioactivity. Note that this differs from any co-purification experiment involving affinity capture in that the co-purification experiment involves at least one extra purification step to get rid of potential contaminating proteins.
Publication
beta -Arrestin-mediated recruitment of the Src family kinase Yes mediates endothelin-1-stimulated glucose transport.
The insulin and the endothelin type A (ETA) receptor both can couple into the heterotrimeric G protein alpha(q/11) (Galpha(q/11)), leading to Galpha(q/11) tyrosine phosphorylation, phosphatidylinositol 3-kinase activation, and subsequent stimulation of glucose transport. In this study, we assessed the potential role of Src kinase in ET-1 signaling to glucose transport in 3T3-L1 adipocytes. Src kinase inhibitor PP2 blocked ET-1-induced Src ... [more]
Throughput
- Low Throughput
Curated By
- BioGRID