BAIT
VKORC1
EDTP308, IMAGE3455200, MST134, MST576, VKCFD2, VKOR, MSTP134
vitamin K epoxide reductase complex, subunit 1
GO Process (7)
GO Function (1)
GO Component (1)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
PREY
CNN3
calponin 3, acidic
GO Process (1)
GO Function (0)
GO Component (3)
Gene Ontology Biological Process
Gene Ontology Cellular Component
Homo sapiens
Two-hybrid
Bait protein expressed as a DNA binding domain (DBD) fusion and prey expressed as a transcriptional activation domain (TAD) fusion and interaction measured by reporter gene activation.
Publication
Identification of VKORC1 interaction partners by split-ubiquitin system and coimmunoprecipitation.
Since the discovery of vitamin K epoxide reductase complex subunit 1 (VKORC1), the key enzyme for the regeneration of vitamin KHâ‚‚, numerous studies have addressed the role of VKORC1 in the posttranslational modification of vitamin K-dependent proteins. VKORC1 is also the target protein of anticoagulant drugs of the coumarin type (e.g. warfarin). Genetic variants in VKORC1 have recently been shown ... [more]
Thromb. Haemost. Feb. 01, 2011; 105(2);285-94 [Pubmed: 21103663]
Throughput
- Low Throughput
Curated By
- BioGRID