BAIT
VKORC1
EDTP308, IMAGE3455200, MST134, MST576, VKCFD2, VKOR, MSTP134
vitamin K epoxide reductase complex, subunit 1
GO Process (7)
GO Function (1)
GO Component (1)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
PREY
CD9
BTCC-1, DRAP-27, MIC3, MRP-1, TSPAN-29, TSPAN29, GIG2
CD9 molecule
GO Process (9)
GO Function (1)
GO Component (7)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
Two-hybrid
Bait protein expressed as a DNA binding domain (DBD) fusion and prey expressed as a transcriptional activation domain (TAD) fusion and interaction measured by reporter gene activation.
Publication
Identification of VKORC1 interaction partners by split-ubiquitin system and coimmunoprecipitation.
Since the discovery of vitamin K epoxide reductase complex subunit 1 (VKORC1), the key enzyme for the regeneration of vitamin KHâ‚‚, numerous studies have addressed the role of VKORC1 in the posttranslational modification of vitamin K-dependent proteins. VKORC1 is also the target protein of anticoagulant drugs of the coumarin type (e.g. warfarin). Genetic variants in VKORC1 have recently been shown ... [more]
Thromb. Haemost. Feb. 01, 2011; 105(2);285-94 [Pubmed: 21103663]
Throughput
- Low Throughput
Curated By
- BioGRID