CSRP2BP
Gene Ontology Biological Process
Gene Ontology Molecular Function
KAT2A
Gene Ontology Biological Process
- alpha-tubulin acetylation [ISO]
- cardiac muscle cell differentiation [ISO]
- cell proliferation [IMP]
- histone H3 acetylation [ISO]
- histone H3-K14 acetylation [IDA]
- histone H4-K12 acetylation [IDA]
- histone deubiquitination [ISO]
- in utero embryonic development [IMP]
- intracellular distribution of mitochondria [ISO]
- metencephalon development [IMP]
- midbrain development [IMP]
- multicellular organism growth [IMP]
- nervous system development [IMP]
- neural tube closure [IMP]
- positive regulation of cell projection organization [ISO]
- positive regulation of gluconeogenesis by positive regulation of transcription from RNA polymerase II promoter [IGI]
- positive regulation of histone acetylation [ISO]
- positive regulation of transcription regulatory region DNA binding [ISO]
- regulation of nucleic acid-templated transcription [ISO]
- regulation of protein stability [ISO]
- somitogenesis [IGI, IMP]
- telencephalon development [IMP]
Gene Ontology Molecular Function- H3 histone acetyltransferase activity [IDA, ISO]
- N-acetyltransferase activity [IDA]
- chromatin binding [IDA, ISO]
- histone acetyltransferase activity [IDA, ISO]
- histone acetyltransferase activity (H4-K12 specific) [IDA]
- histone deacetylase binding [ISO]
- protein binding [IPI]
- protein phosphatase binding [ISO]
- transcription coactivator activity [ISO]
- H3 histone acetyltransferase activity [IDA, ISO]
- N-acetyltransferase activity [IDA]
- chromatin binding [IDA, ISO]
- histone acetyltransferase activity [IDA, ISO]
- histone acetyltransferase activity (H4-K12 specific) [IDA]
- histone deacetylase binding [ISO]
- protein binding [IPI]
- protein phosphatase binding [ISO]
- transcription coactivator activity [ISO]
Gene Ontology Cellular Component
Affinity Capture-Western
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner identified by Western blot with a specific polyclonal antibody or second epitope tag. This category is also used if an interacting protein is visualized directly by dye stain or radioactivity. Note that this differs from any co-purification experiment involving affinity capture in that the co-purification experiment involves at least one extra purification step to get rid of potential contaminating proteins.
Publication
The double-histone-acetyltransferase complex ATAC is essential for mammalian development.
Acetylation of the histone tails, catalyzed by histone acetyltransferases (HATs), is a well-studied process that contributes to transcriptionally active chromatin states. Here we report the characterization of a novel mammalian HAT complex, which contains the two acetyltransferases GCN5 and ATAC2 as well as other proteins linked to chromatin metabolism. This multisubunit complex has a similar but distinct subunit composition to ... [more]
Throughput
- Low Throughput
Related interactions
| Interaction | Experimental Evidence Code | Dataset | Throughput | Score | Curated By | Notes |
|---|---|---|---|---|---|---|
| CSRP2BP KAT2A | Affinity Capture-MS Affinity Capture-MS An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods. | Low | - | BioGRID | - | |
| KAT2A CSRP2BP | Affinity Capture-Western Affinity Capture-Western An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner identified by Western blot with a specific polyclonal antibody or second epitope tag. This category is also used if an interacting protein is visualized directly by dye stain or radioactivity. Note that this differs from any co-purification experiment involving affinity capture in that the co-purification experiment involves at least one extra purification step to get rid of potential contaminating proteins. | Low | - | BioGRID | - | |
| CSRP2BP KAT2A | Co-fractionation Co-fractionation Interaction inferred from the presence of two or more protein subunits in a partially purified protein preparation. If co-fractionation is demonstrated between 3 or more proteins, then add them as a complex. | Low | - | BioGRID | - |
Curated By
- BioGRID