BAIT
KCNC1
C230009H10Rik, KShIIIB, KV4, Kcr2-1, Kv3.1, NGK2, Shaw
potassium voltage gated channel, Shaw-related subfamily, member 1
GO Process (2)
GO Function (2)
GO Component (4)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Mus musculus
PREY
KIF5B
AL022807, Khc, Khcs, Kns1, Ukhc
kinesin family member 5B
GO Process (14)
GO Function (5)
GO Component (12)
Gene Ontology Biological Process
- ATP catabolic process [IBA]
- axon guidance [IBA]
- cytoplasm organization [IMP]
- metabolic process [ISO]
- microtubule-based process [TAS]
- mitochondrial transport [TAS]
- plus-end-directed vesicle transport along microtubule [IMP]
- positive regulation of establishment of protein localization to plasma membrane [ISO]
- positive regulation of potassium ion transport [ISO]
- positive regulation of synaptic transmission, GABAergic [IDA]
- protein localization [IBA]
- regulation of membrane potential [ISO]
- stress granule disassembly [IMP]
- vesicle transport along microtubule [IGI, ISO]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Mus musculus
FRET
An interaction is inferred when close proximity of interaction partners is detected by fluorescence resonance energy transfer between pairs of fluorophore-labeled molecules, such as occurs between CFP (donor) and YFP (acceptor) fusion proteins.
Publication
Kinesin I transports tetramerized Kv3 channels through the axon initial segment via direct binding.
Precise targeting of various voltage-gated ion channels to proper membrane domains is crucial for their distinct roles in neuronal excitability and synaptic transmission. How each channel protein is transported within the cytoplasm is poorly understood. Here, we report that KIF5/kinesin I transports Kv3.1 voltage-gated K(+) (Kv) channels through the axon initial segment (AIS) via direct binding. First, we have identified ... [more]
J. Neurosci. Nov. 24, 2010; 30(47);15987-6001 [Pubmed: 21106837]
Throughput
- Low Throughput
Curated By
- BioGRID