BAIT
SNAP23
synaptosomal-associated protein 23
GO Process (9)
GO Function (3)
GO Component (12)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Rattus norvegicus
PREY
STX1B
Stx1b2, Stx2
syntaxin 1B
GO Process (11)
GO Function (4)
GO Component (6)
Gene Ontology Biological Process
- intracellular protein transport [IBA]
- positive regulation of excitatory postsynaptic membrane potential [ISS]
- positive regulation of neurotransmitter secretion [ISS]
- protein transport [IMP]
- regulation of exocytosis [IMP]
- regulation of gene expression [ISS]
- regulation of synaptic vesicle priming [ISS]
- synaptic vesicle docking [ISS]
- synaptic vesicle fusion to presynaptic membrane [IBA]
- vesicle docking [IBA]
- vesicle-mediated transport [IMP]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Rattus norvegicus
Two-hybrid
Bait protein expressed as a DNA binding domain (DBD) fusion and prey expressed as a transcriptional activation domain (TAD) fusion and interaction measured by reporter gene activation.
Publication
Hrs interacts with SNAP-25 and regulates Ca(2+)-dependent exocytosis.
Synaptosome-associated protein of 25 kDa (SNAP-25) is a neuronal membrane protein essential for synaptic vesicle exocytosis. To investigate the mechanisms by which SNAP-25 mediates neurosecretion, we performed a search for proteins that interact with SNAP-25 using a yeast two-hybrid screen. Here, we report the isolation and characterization of a SNAP-25-interacting protein that is the rat homologue of mouse hepatocyte growth ... [more]
J. Cell. Sci. Jun. 01, 2000; 113(0);2273-84 [Pubmed: 10825299]
Throughput
- Low Throughput
Curated By
- BioGRID