BAIT
SYP
Syp1
synaptophysin
GO Process (6)
GO Function (7)
GO Component (13)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
- excitatory synapse [IDA, ISO]
- integral component of synaptic vesicle membrane [IBA, TAS]
- intracellular organelle [IDA]
- membrane [ISO]
- neuron projection [IDA]
- neuron projection terminus [IDA, ISO]
- presynaptic active zone [ISO]
- presynaptic membrane [ISO]
- protein complex [IDA]
- synapse [ISO]
- synaptic vesicle [IDA, ISO]
- synaptic vesicle membrane [ISO]
- terminal bouton [IDA]
Rattus norvegicus
PREY
SNAP25
SNAP-25B, SNAP-25a
synaptosomal-associated protein 25
GO Process (17)
GO Function (9)
GO Component (28)
Gene Ontology Biological Process
- axonogenesis [IEP]
- calcium ion-dependent exocytosis of neurotransmitter [IDA]
- endosomal transport [IDA]
- exocytosis [TAS]
- growth hormone secretion [IEP]
- long-term memory [IMP]
- long-term synaptic potentiation [ISO]
- neurotransmitter secretion [ISO]
- positive regulation of hormone secretion [IMP]
- positive regulation of insulin secretion [IEP]
- potassium ion transmembrane transport [IDA]
- regulation of establishment of protein localization [ISO]
- regulation of neuron projection development [IMP]
- regulation of synapse assembly [IEP]
- sleep [IDA]
- synaptic vesicle fusion to presynaptic membrane [IBA]
- synaptic vesicle priming [IBA]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
- BLOC-1 complex [ISO, ISS]
- SNARE complex [IDA, ISO]
- actin cytoskeleton [IDA]
- axon [IDA]
- axonal growth cone [IDA]
- cell [ISO]
- cytoplasm [IDA, ISO]
- cytosol [IDA]
- endosome [IDA]
- filopodium [IDA]
- growth cone [IDA]
- intracellular organelle [IDA]
- lamellipodium [IDA]
- membrane [ISO, ISS]
- membrane raft [IDA]
- myelin sheath [ISO]
- neuron projection [IDA]
- neuronal cell body [IDA]
- perinuclear region of cytoplasm [ISO]
- plasma membrane [IDA]
- synapse [ISO]
- synaptobrevin 2-SNAP-25-syntaxin-1a complex [IDA]
- synaptobrevin 2-SNAP-25-syntaxin-1a-complexin I complex [IDA, ISO]
- synaptobrevin 2-SNAP-25-syntaxin-1a-complexin II complex [IDA]
- terminal bouton [IDA]
- trans-Golgi network [ISO]
- vesicle [ISO]
- voltage-gated potassium channel complex [IDA]
Rattus norvegicus
Co-fractionation
Interaction inferred from the presence of two or more protein subunits in a partially purified protein preparation. If co-fractionation is demonstrated between 3 or more proteins, then add them as a complex.
Publication
Hrs interacts with SNAP-25 and regulates Ca(2+)-dependent exocytosis.
Synaptosome-associated protein of 25 kDa (SNAP-25) is a neuronal membrane protein essential for synaptic vesicle exocytosis. To investigate the mechanisms by which SNAP-25 mediates neurosecretion, we performed a search for proteins that interact with SNAP-25 using a yeast two-hybrid screen. Here, we report the isolation and characterization of a SNAP-25-interacting protein that is the rat homologue of mouse hepatocyte growth ... [more]
J. Cell. Sci. Jun. 01, 2000; 113(0);2273-84 [Pubmed: 10825299]
Throughput
- Low Throughput
Curated By
- BioGRID