BAIT
CAV3
AI385751, Cav-3, M-cav
caveolin 3
GO Process (54)
GO Function (12)
GO Component (17)
Gene Ontology Biological Process
- actin filament organization [IMP]
- cardiac muscle cell development [IMP]
- caveola assembly [IMP, ISO]
- cholesterol homeostasis [IMP]
- cytoplasmic microtubule organization [IMP]
- endocytosis [IMP, TAS]
- establishment of protein localization to plasma membrane [IMP]
- glucose homeostasis [IMP]
- heart trabecula formation [IMP]
- membrane raft organization [IMP]
- muscle cell cellular homeostasis [IMP]
- myoblast fusion [IMP]
- myotube differentiation [IMP]
- negative regulation of MAP kinase activity [ISO]
- negative regulation of MAPK cascade [IMP]
- negative regulation of calcium ion transport [IMP, ISO]
- negative regulation of cardiac muscle hypertrophy [IMP, ISO]
- negative regulation of cell growth involved in cardiac muscle cell development [ISO]
- negative regulation of cell size [ISO]
- negative regulation of nitric-oxide synthase activity [IMP]
- negative regulation of potassium ion transmembrane transport [ISO]
- negative regulation of potassium ion transmembrane transporter activity [ISO]
- negative regulation of protein kinase activity [IMP]
- negative regulation of sarcomere organization [ISO]
- nucleus localization [IMP]
- plasma membrane organization [IMP]
- plasma membrane repair [IMP]
- positive regulation of caveolin-mediated endocytosis [ISO]
- positive regulation of cell proliferation [ISO]
- positive regulation of cytosolic calcium ion concentration [ISO]
- positive regulation of microtubule polymerization [ISO]
- positive regulation of myotube differentiation [IMP]
- protein localization [IGI, IMP]
- protein localization to plasma membrane [IMP]
- regulation of branching involved in mammary gland duct morphogenesis [IMP]
- regulation of calcium ion import [ISO]
- regulation of calcium ion transmembrane transporter activity [ISO]
- regulation of calcium ion transport [IMP]
- regulation of cardiac muscle contraction [ISO]
- regulation of heart contraction [ISO]
- regulation of heart rate [ISO]
- regulation of membrane depolarization during cardiac muscle cell action potential [ISO]
- regulation of membrane potential [IGI, ISO]
- regulation of nerve growth factor receptor activity [ISO]
- regulation of p38MAPK cascade [IMP]
- regulation of protein kinase B signaling [IMP]
- regulation of signal transduction by receptor internalization [ISO]
- regulation of skeletal muscle contraction [ISO]
- regulation of sodium ion transmembrane transporter activity [ISO]
- regulation of transforming growth factor beta receptor signaling pathway [IMP]
- regulation of ventricular cardiac muscle cell membrane depolarization [ISO]
- regulation of ventricular cardiac muscle cell membrane repolarization [ISO]
- triglyceride metabolic process [IMP]
- ventricular cardiac muscle cell action potential [ISO]
Gene Ontology Molecular Function- alpha-tubulin binding [IDA]
- calcium channel regulator activity [ISO]
- connexin binding [IPI, ISO]
- enzyme binding [ISO]
- ion channel binding [IPI, ISO]
- nitric-oxide synthase binding [ISO]
- potassium channel inhibitor activity [ISO]
- protein C-terminus binding [ISO]
- protein binding [IPI]
- protein complex binding [ISO]
- protein complex scaffold [ISO]
- sodium channel regulator activity [ISO]
- alpha-tubulin binding [IDA]
- calcium channel regulator activity [ISO]
- connexin binding [IPI, ISO]
- enzyme binding [ISO]
- ion channel binding [IPI, ISO]
- nitric-oxide synthase binding [ISO]
- potassium channel inhibitor activity [ISO]
- protein C-terminus binding [ISO]
- protein binding [IPI]
- protein complex binding [ISO]
- protein complex scaffold [ISO]
- sodium channel regulator activity [ISO]
Gene Ontology Cellular Component
- T-tubule [IDA, ISO]
- Z disc [ISO]
- caveola [IDA, ISO]
- cell [IMP]
- cell surface [ISO]
- cytoplasm [ISO]
- cytosol [ISO]
- dystrophin-associated glycoprotein complex [ISO]
- endoplasmic reticulum [ISO]
- intercalated disc [ISO]
- membrane [IDA]
- membrane raft [IDA]
- neuromuscular junction [ISO]
- plasma membrane [IDA, ISO]
- protein complex [ISO]
- sarcolemma [IDA, ISO]
- vesicle [ISO]
Mus musculus
PREY
DAG1
D9Wsu13e, DG, Dp427, Dp71
dystroglycan 1
GO Process (17)
GO Function (9)
GO Component (22)
Gene Ontology Biological Process
- NLS-bearing protein import into nucleus [ISO]
- Schwann cell development [IMP]
- basement membrane organization [IMP]
- branching involved in salivary gland morphogenesis [IMP]
- calcium-dependent cell-matrix adhesion [ISO]
- commissural neuron axon guidance [IMP]
- cytoskeletal anchoring at plasma membrane [ISO]
- epithelial tube branching involved in lung morphogenesis [IMP]
- membrane protein ectodomain proteolysis [ISO]
- microtubule anchoring [ISO]
- modulation by virus of host morphology or physiology [ISO]
- morphogenesis of an epithelial sheet [IMP]
- myelination in peripheral nervous system [IMP]
- negative regulation of MAPK cascade [ISO]
- negative regulation of cell migration [ISO]
- negative regulation of protein kinase B signaling [ISO]
- nerve maturation [IMP]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
- basement membrane [IDA, ISO]
- basolateral plasma membrane [ISO]
- cell outer membrane [IDA]
- cell-cell adherens junction [ISO]
- cell-cell junction [IDA]
- contractile ring [ISO]
- costamere [ISO]
- cytoplasm [ISO]
- dystroglycan complex [IDA]
- dystrophin-associated glycoprotein complex [ISO]
- extracellular space [ISO]
- extracellular vesicular exosome [ISO]
- filopodium [ISO]
- focal adhesion [ISO]
- integral component of membrane [ISO]
- lamellipodium [ISO]
- membrane [IDA]
- membrane raft [IDA]
- node of Ranvier [IMP]
- nucleoplasm [ISO]
- plasma membrane [IDA, ISO]
- sarcolemma [IDA, ISO]
Mus musculus
Co-fractionation
Interaction inferred from the presence of two or more protein subunits in a partially purified protein preparation. If co-fractionation is demonstrated between 3 or more proteins, then add them as a complex.
Publication
Expression of caveolin-3 in skeletal, cardiac, and smooth muscle cells. Caveolin-3 is a component of the sarcolemma and co-fractionates with dystrophin and dystrophin-associated glycoproteins.
Caveolae are microdomains of the plasma membrane that have been implicated in signal transduction. Caveolin, a 21-24-kDa integral membrane protein, is a principal component of the caveolae membrane. Recently, we and others have identified a family of caveolin-related proteins; caveolin has been retermed caveolin-1. Caveolin-3 is most closely related to caveolin-1, but caveolin-3 mRNA is expressed only in muscle tissue ... [more]
J. Biol. Chem. Jun. 21, 1996; 271(25);15160-5 [Pubmed: 8663016]
Throughput
- Low Throughput
Curated By
- BioGRID