Co-fractionation

Interaction inferred from the presence of two or more protein subunits in a partially purified protein preparation. If co-fractionation is demonstrated between 3 or more proteins, then add them as a complex.

Publication

Biochemical characterization of the native Kv2.1 potassium channel.

Chung JJ, Li M

Functional diversity of potassium channels in both prokaryotic and eukaryotic cells suggests multiple levels of regulation. Posttranslational regulation includes differential subunit assembly of homologous pore-forming subunits. In addition, a variety of modulatory subunits may interact with the pore complex either statically or dynamically. Kv2.1 is a delayed rectifier potassium channel isolated by expression cloning. The native polypeptide has not been ... [more]

FEBS J. Jul. 01, 2005; 272(14);3743-55 [Pubmed: 16008572]

Throughput

  • Low Throughput

Curated By

  • BioGRID