BAIT
RALA
v-ral simian leukemia viral oncogene homolog A (ras related)
GO Process (4)
GO Function (2)
GO Component (9)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Rattus norvegicus
PREY
RALBP1
ralA binding protein 1
GO Process (9)
GO Function (7)
GO Component (2)
Gene Ontology Biological Process
- ATP catabolic process [ISO]
- endocytosis [IMP]
- mitotic spindle organization [IDA]
- negative regulation of smooth muscle cell proliferation [IMP]
- positive regulation of Cdc42 GTPase activity [ISO]
- positive regulation of Rac GTPase activity [ISO]
- regulation of GTPase activity [ISO]
- small GTPase mediated signal transduction [IPI, ISO]
- transport [ISO]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Rattus norvegicus
Two-hybrid
Bait protein expressed as a DNA binding domain (DBD) fusion and prey expressed as a transcriptional activation domain (TAD) fusion and interaction measured by reporter gene activation.
Publication
RalA interacts with ZONAB in a cell density-dependent manner and regulates its transcriptional activity.
Ral proteins are members of the Ras superfamily of small GTPases and are involved in signalling pathways for actin cytoskeleton remodelling, cell cycle control, cellular transformation and vesicle transport. To identify novel RalA effector proteins, we used the reverse Ras recruitment system and found that RalA interacts with a Y-box transcription factor, ZO-1-associated nucleic acid-binding protein (ZONAB), in a GTP-dependent ... [more]
EMBO J. Jan. 12, 2005; 24(1);54-62 [Pubmed: 15592429]
Throughput
- Low Throughput
Curated By
- BioGRID