CTBP2
Gene Ontology Biological Process
- negative regulation of transcription, DNA-templated [IDA, IPI]
- positive regulation of chromatin binding [IMP]
- positive regulation of retinoic acid receptor signaling pathway [IMP, ISO]
- positive regulation of transcription from RNA polymerase II promoter [IGI, IMP, ISO]
- white fat cell differentiation [IDA]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
ZFPM1
Gene Ontology Biological Process
- atrial septum morphogenesis [IMP]
- atrioventricular valve morphogenesis [IMP]
- cardiac muscle tissue morphogenesis [IMP]
- definitive erythrocyte differentiation [IMP]
- embryonic hemopoiesis [IMP]
- erythrocyte differentiation [IGI, IMP]
- granulocyte differentiation [IMP]
- heart development [IMP]
- homeostasis of number of cells [IMP]
- megakaryocyte development [IMP]
- megakaryocyte differentiation [IGI, IMP]
- mitral valve formation [IMP]
- negative regulation of fat cell differentiation [IMP]
- negative regulation of interleukin-4 biosynthetic process [ISO]
- negative regulation of mast cell differentiation [IDA]
- negative regulation of protein binding [IDA]
- negative regulation of transcription from RNA polymerase II promoter [IBA, IDA, IMP, ISO, TAS]
- outflow tract morphogenesis [IMP]
- platelet formation [ISO]
- positive regulation of interferon-gamma biosynthetic process [ISO]
- positive regulation of transcription from RNA polymerase II promoter [IDA]
- primitive erythrocyte differentiation [IMP]
- regulation of chemokine production [IMP]
- regulation of definitive erythrocyte differentiation [ISO]
- transcription from RNA polymerase II promoter [IBA]
- transcriptional activation by promoter-enhancer looping [IDA]
- tricuspid valve formation [IMP]
- ventricular septum morphogenesis [IMP]
Gene Ontology Molecular Function- RNA polymerase II activating transcription factor binding [IDA]
- RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription [IBA, ISO]
- RNA polymerase II transcription factor binding [ISO]
- protein binding [IPI]
- transcription corepressor activity [TAS]
- transcription factor binding [ISO]
- RNA polymerase II activating transcription factor binding [IDA]
- RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription [IBA, ISO]
- RNA polymerase II transcription factor binding [ISO]
- protein binding [IPI]
- transcription corepressor activity [TAS]
- transcription factor binding [ISO]
Gene Ontology Cellular Component
Affinity Capture-Western
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner identified by Western blot with a specific polyclonal antibody or second epitope tag. This category is also used if an interacting protein is visualized directly by dye stain or radioactivity. Note that this differs from any co-purification experiment involving affinity capture in that the co-purification experiment involves at least one extra purification step to get rid of potential contaminating proteins.
Publication
Interaction between FOG-1 and the corepressor C-terminal binding protein is dispensable for normal erythropoiesis in vivo.
The hematopoietic, zinc-finger protein FOG-1 is essential for the development of the erythroid and megakaryocytic lineages. FOG-1's function in hematopoiesis is dependent on its ability to interact with the transcription factor GATA-1. FOG-1 has also been observed to interact with the corepressor molecule C-terminal binding protein (CtBP) through a peptide motif shared by all FOG family members. In this study, ... [more]
Throughput
- Low Throughput
Related interactions
| Interaction | Experimental Evidence Code | Dataset | Throughput | Score | Curated By | Notes |
|---|---|---|---|---|---|---|
| ZFPM1 CTBP2 | Affinity Capture-MS Affinity Capture-MS An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods. | Low | - | BioGRID | - | |
| ZFPM1 CTBP2 | Affinity Capture-Western Affinity Capture-Western An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner identified by Western blot with a specific polyclonal antibody or second epitope tag. This category is also used if an interacting protein is visualized directly by dye stain or radioactivity. Note that this differs from any co-purification experiment involving affinity capture in that the co-purification experiment involves at least one extra purification step to get rid of potential contaminating proteins. | Low | - | BioGRID | - |
Curated By
- BioGRID