FIZ1
Gene Ontology Biological Process
Gene Ontology Molecular Function
FLT3
Gene Ontology Biological Process
- B cell differentiation [IMP, ISO]
- cellular response to cytokine stimulus [IMP, ISO]
- common myeloid progenitor cell proliferation [IMP, ISO]
- cytokine-mediated signaling pathway [IMP, ISO]
- dendritic cell differentiation [IMP, ISO]
- hemopoiesis [ISO]
- leukocyte homeostasis [IMP, ISO]
- lymphocyte differentiation [IDA]
- lymphocyte proliferation [IMP, ISO]
- lymphoid progenitor cell differentiation [IGI]
- myeloid progenitor cell differentiation [IGI, IMP, ISO]
- negative regulation of B cell differentiation [IDA]
- negative regulation of cell proliferation [IMP]
- peptidyl-tyrosine phosphorylation [IDA, ISO]
- positive regulation of protein phosphorylation [IGI]
- pro-B cell differentiation [IMP, ISO]
- pro-T cell differentiation [IMP]
- protein autophosphorylation [IDA]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Affinity Capture-Western
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner identified by Western blot with a specific polyclonal antibody or second epitope tag. This category is also used if an interacting protein is visualized directly by dye stain or radioactivity. Note that this differs from any co-purification experiment involving affinity capture in that the co-purification experiment involves at least one extra purification step to get rid of potential contaminating proteins.
Publication
Fiz1, a novel zinc finger protein interacting with the receptor tyrosine kinase Flt3.
The receptor tyrosine kinase Flt3 has been shown to play a role in proliferation and survival of hematopoietic progenitor cells as well as differentiation of early B lymphoid progenitors. However, the signaling events that control growth or differentiation are not completely understood. In order to identify new signaling molecules interacting with the cytoplasmic domain of Flt3, we performed a yeast ... [more]
Throughput
- Low Throughput
Curated By
- BioGRID