APBB2
Gene Ontology Biological Process
- actin filament-based movement [NAS]
- axon guidance [IGI]
- cell cycle arrest [IDA]
- extracellular matrix organization [IGI]
- negative regulation of apoptotic process [IGI]
- negative regulation of cell growth [IDA]
- neuron migration [IGI]
- positive regulation of apoptotic process [IDA]
- protein stabilization [NAS]
- regulation of transcription, DNA-templated [IDA]
Gene Ontology Molecular Function
APBB2
Gene Ontology Biological Process
- actin filament-based movement [NAS]
- axon guidance [IGI]
- cell cycle arrest [IDA]
- extracellular matrix organization [IGI]
- negative regulation of apoptotic process [IGI]
- negative regulation of cell growth [IDA]
- neuron migration [IGI]
- positive regulation of apoptotic process [IDA]
- protein stabilization [NAS]
- regulation of transcription, DNA-templated [IDA]
Gene Ontology Molecular Function
Affinity Capture-Western
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner identified by Western blot with a specific polyclonal antibody or second epitope tag. This category is also used if an interacting protein is visualized directly by dye stain or radioactivity. Note that this differs from any co-purification experiment involving affinity capture in that the co-purification experiment involves at least one extra purification step to get rid of potential contaminating proteins.
Publication
Cloning and characterization of a small-size peptide Zfra that regulates the cytotoxic function of tumor necrosis factor by interacting with JNK1.
By cDNA library screening, here we isolated an unusual gene transcript encoding a 31-amino-acid zinc finger-like peptide that regulates apoptosis (named Zfra). Northern blotting and RT/PCR showed the transcript is abundant in spleen but absent in several prostate and breast cancer cells. When stably expressed in L929 fibroblasts, Zfra conferred resistance to the cytotoxic effects of TNF and FasL. In ... [more]
Throughput
- Low Throughput
Curated By
- BioGRID