BAIT
DAB1
AI956902, C630028C02Rik, scm, scr, scrambler, yot, RP23-356E21.1
disabled 1
GO Process (20)
GO Function (4)
GO Component (9)
Gene Ontology Biological Process
- Golgi localization [IMP]
- adult walking behavior [IMP]
- cell-cell adhesion involved in neuronal-glial interactions involved in cerebral cortex radial glia guided migration [IMP]
- central nervous system development [TAS]
- cerebellum structural organization [IMP]
- cerebral cortex cell migration [IMP]
- cerebral cortex radially oriented cell migration [IGI, IMP, ISO]
- dendrite development [IGI, IMP]
- intracellular signal transduction [TAS]
- lateral motor column neuron migration [IMP]
- negative regulation of JAK-STAT cascade [IMP]
- negative regulation of astrocyte differentiation [IMP]
- negative regulation of axonogenesis [IGI, IMP]
- negative regulation of cell adhesion [IMP]
- nervous system development [NAS]
- neuron migration [IGI, IMP, ISO]
- positive regulation of neuron differentiation [IMP]
- positive regulation of protein kinase activity [IGI]
- radial glia guided migration of Purkinje cell [IGI, IMP]
- small GTPase mediated signal transduction [IMP]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Mus musculus
PREY
YES1
Yes, p61-Yes
Yamaguchi sarcoma viral (v-yes) oncogene homolog 1
GO Process (13)
GO Function (7)
GO Component (7)
Gene Ontology Biological Process
- cell differentiation [IBA]
- cellular response to peptide hormone stimulus [IBA]
- cellular response to platelet-derived growth factor stimulus [IDA]
- cellular response to retinoic acid [IDA]
- cellular response to transforming growth factor beta stimulus [IGI]
- glucose transport [IDA]
- innate immune response [IBA]
- peptidyl-tyrosine autophosphorylation [IBA]
- positive regulation of peptidyl-tyrosine phosphorylation [IDA]
- positive regulation of transcription from RNA polymerase II promoter [IGI]
- protein autophosphorylation [ISO]
- regulation of cell proliferation [IBA]
- transmembrane receptor protein tyrosine kinase signaling pathway [IBA]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Mus musculus
Affinity Capture-MS
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.
Publication
Activation of a Dab1/CrkL/C3G/Rap1 pathway in Reelin-stimulated neurons.
During brain development, many neurons migrate long distances before settling and differentiating. These migrations are coordinated to ensure normal development. The secreted protein Reelin controls the locations of many types of neurons, and its absence causes the classic "Reeler" phenotype. Reelin action requires tyrosine phosphorylation of the intracellular protein Dab1 by Src-family kinases. However, little is known about signaling pathways ... [more]
Curr. Biol. Apr. 06, 2004; 14(7);606-10 [Pubmed: 15062102]
Throughput
- Low Throughput
Curated By
- BioGRID