RARG
Gene Ontology Biological Process
- Harderian gland development [IMP]
- anterior/posterior pattern specification [IGI, IMP]
- bone development [IGI, IMP]
- bone morphogenesis [IGI, IMP]
- camera-type eye development [IGI]
- cellular response to retinoic acid [IDA]
- chondrocyte development [IMP]
- embryonic camera-type eye development [IGI]
- embryonic eye morphogenesis [IGI]
- embryonic hindlimb morphogenesis [IGI]
- epithelium development [IMP]
- face development [IGI]
- gland development [IMP]
- glandular epithelial cell development [IGI]
- growth plate cartilage chondrocyte growth [IMP]
- growth plate cartilage development [IGI]
- limb development [IGI, IMP]
- multicellular organism growth [IGI]
- negative regulation of apoptotic process [IGI]
- negative regulation of cartilage development [IMP]
- negative regulation of cell differentiation [IMP]
- negative regulation of cell proliferation [IGI]
- negative regulation of chondrocyte differentiation [IMP]
- negative regulation of transcription from RNA polymerase II promoter [IDA]
- neural tube closure [IGI]
- positive regulation of apoptotic process [IGI]
- positive regulation of cell proliferation [IGI, ISO]
- positive regulation of gene expression [IDA]
- positive regulation of programmed cell death [IGI]
- positive regulation of transcription from RNA polymerase II promoter [IC, IDA, IGI]
- prostate gland epithelium morphogenesis [IMP]
- regulation of gene expression [IGI]
- regulation of myelination [ISO]
- regulation of transcription from RNA polymerase II promoter [ISO]
- reproductive structure development [IMP]
- response to retinoic acid [ISO]
- retina development in camera-type eye [IGI]
- retinal pigment epithelium development [IGI]
- retinoic acid receptor signaling pathway [IMP, ISO]
- trachea cartilage development [IMP]
- transcription from RNA polymerase II promoter [ISO]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
PUS1
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Affinity Capture-Western
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner identified by Western blot with a specific polyclonal antibody or second epitope tag. This category is also used if an interacting protein is visualized directly by dye stain or radioactivity. Note that this differs from any co-purification experiment involving affinity capture in that the co-purification experiment involves at least one extra purification step to get rid of potential contaminating proteins.
Publication
Regulation of nuclear receptor activity by a pseudouridine synthase through posttranscriptional modification of steroid receptor RNA activator.
Nuclear receptors (NRs) induce transcription through association with coactivator complexes. We identified a pseudouridine synthase (PUS), mPus1p, as a coactivator for retinoic acid receptor (mRAR)gamma and other NR-dependent transactivation. mPus1p is a member of the truA subfamily of PUSs, a class of enzymes that isomerize uridine to pseudouridine in noncoding RNAs, such as tRNA, to ensure proper folding and function. ... [more]
Throughput
- Low Throughput
Related interactions
| Interaction | Experimental Evidence Code | Dataset | Throughput | Score | Curated By | Notes |
|---|---|---|---|---|---|---|
| PUS1 RARG | Affinity Capture-Western Affinity Capture-Western An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner identified by Western blot with a specific polyclonal antibody or second epitope tag. This category is also used if an interacting protein is visualized directly by dye stain or radioactivity. Note that this differs from any co-purification experiment involving affinity capture in that the co-purification experiment involves at least one extra purification step to get rid of potential contaminating proteins. | Low | - | BioGRID | - | |
| RARG PUS1 | Co-fractionation Co-fractionation Interaction inferred from the presence of two or more protein subunits in a partially purified protein preparation. If co-fractionation is demonstrated between 3 or more proteins, then add them as a complex. | High | 0.925 | BioGRID | 2684492 |
Curated By
- BioGRID