UBC
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
PEX5
Gene Ontology Biological Process
- cell development [ISO]
- cellular lipid metabolic process [ISO]
- cerebral cortex cell migration [ISO]
- cerebral cortex neuron differentiation [ISO]
- endoplasmic reticulum organization [ISO]
- fatty acid beta-oxidation [ISO]
- isoprenoid biosynthetic process [ISO]
- mitochondrial membrane organization [ISO]
- mitochondrion organization [ISO]
- negative regulation of protein homotetramerization [ISO]
- neuromuscular process [ISO]
- neuron migration [ISO]
- peroxisome organization [ISO]
- positive regulation of multicellular organism growth [ISO]
- protein import into peroxisome matrix [IBA, ISO]
- protein import into peroxisome matrix, docking [IBA, ISO]
- protein import into peroxisome matrix, translocation [ISO]
- protein import into peroxisome membrane [ISO]
- protein targeting to peroxisome [ISO]
- protein tetramerization [ISO]
- very long-chain fatty acid metabolic process [ISO]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Affinity Capture-Western
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner identified by Western blot with a specific polyclonal antibody or second epitope tag. This category is also used if an interacting protein is visualized directly by dye stain or radioactivity. Note that this differs from any co-purification experiment involving affinity capture in that the co-purification experiment involves at least one extra purification step to get rid of potential contaminating proteins.
Publication
Ubiquitination of mammalian Pex5p, the peroxisomal import receptor.
Protein translocation across the peroxisomal membrane requires the concerted action of numerous peroxins. One central component of this machinery is Pex5p, the cycling receptor for matrix proteins. Pex5p recognizes newly synthesized proteins in the cytosol and promotes their translocation across the peroxisomal membrane. After this translocation step, Pex5p is recycled back into the cytosol to start a new protein transport ... [more]
Throughput
- Low Throughput
Related interactions
| Interaction | Experimental Evidence Code | Dataset | Throughput | Score | Curated By | Notes |
|---|---|---|---|---|---|---|
| UBC PEX5 | Affinity Capture-Western Affinity Capture-Western An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner identified by Western blot with a specific polyclonal antibody or second epitope tag. This category is also used if an interacting protein is visualized directly by dye stain or radioactivity. Note that this differs from any co-purification experiment involving affinity capture in that the co-purification experiment involves at least one extra purification step to get rid of potential contaminating proteins. | Low | - | BioGRID | 685292 |
Curated By
- BioGRID