MAP1B
Gene Ontology Biological Process
- axon extension [IMP]
- axonogenesis [IGI]
- cellular process [ISO]
- dendrite development [IMP]
- establishment of monopolar cell polarity [IMP]
- microtubule bundle formation [IMP, ISO]
- microtubule-based process [TAS]
- mitochondrion transport along microtubule [IMP]
- negative regulation of intracellular transport [IMP]
- negative regulation of microtubule depolymerization [ISO]
- positive regulation of axon extension [IMP, ISO]
- positive regulation of microtubule polymerization [ISO]
- positive regulation of neuron differentiation [ISO]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
- axon [ISO]
- cell [IMP]
- cytoplasm [ISO]
- cytoskeleton [ISO]
- cytosol [IDA]
- dendrite [ISO]
- growth cone [ISO]
- intracellular [IMP]
- microtubule associated complex [ISO, TAS]
- neuronal cell body [ISO]
- neuronal postsynaptic density [IDA]
- perikaryon [ISO]
- perinuclear region of cytoplasm [ISO]
- photoreceptor outer segment [IDA]
- plasma membrane [ISO]
- postsynaptic density [IDA, ISO]
NXF1
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Affinity Capture-Western
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner identified by Western blot with a specific polyclonal antibody or second epitope tag. This category is also used if an interacting protein is visualized directly by dye stain or radioactivity. Note that this differs from any co-purification experiment involving affinity capture in that the co-purification experiment involves at least one extra purification step to get rid of potential contaminating proteins.
Publication
Nuclear export factor family protein participates in cytoplasmic mRNA trafficking.
In eukaryotes, the nuclear export of mRNA is mediated by nuclear export factor 1 (NXF1) receptors. Metazoans encode additional NXF1-related proteins of unknown function, which share homology and domain organization with NXF1. Some mammalian NXF1-related genes are expressed preferentially in the brain and are thought to participate in neuronal mRNA metabolism. To address the roles of NXF1-related factors, we studied ... [more]
Throughput
- Low Throughput
Related interactions
| Interaction | Experimental Evidence Code | Dataset | Throughput | Score | Curated By | Notes |
|---|---|---|---|---|---|---|
| NXF1 MAP1B | Two-hybrid Two-hybrid Bait protein expressed as a DNA binding domain (DBD) fusion and prey expressed as a transcriptional activation domain (TAD) fusion and interaction measured by reporter gene activation. | Low | - | BioGRID | - |
Curated By
- BioGRID