LSM7
Gene Ontology Biological Process
Gene Ontology Molecular Function
SNRPD3
Gene Ontology Biological Process
- RNA metabolic process [TAS]
- RNA splicing [TAS]
- gene expression [TAS]
- histone mRNA metabolic process [TAS]
- mRNA 3'-end processing [TAS]
- mRNA splicing, via spliceosome [IC, TAS]
- ncRNA metabolic process [TAS]
- spliceosomal snRNP assembly [IDA, TAS]
- termination of RNA polymerase II transcription [TAS]
- transcription from RNA polymerase II promoter [TAS]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
- SMN-Sm protein complex [IDA]
- U1 snRNP [IDA]
- U12-type spliceosomal complex [IDA]
- U4 snRNP [IDA]
- U7 snRNP [IDA]
- catalytic step 2 spliceosome [IDA]
- cytoplasm [IDA]
- cytosol [IDA, TAS]
- extracellular vesicular exosome [IDA]
- methylosome [IDA]
- nucleoplasm [IDA, TAS]
- pICln-Sm protein complex [IDA]
- small nuclear ribonucleoprotein complex [TAS]
- spliceosomal complex [TAS]
Two-hybrid
Bait protein expressed as a DNA binding domain (DBD) fusion and prey expressed as a transcriptional activation domain (TAD) fusion and interaction measured by reporter gene activation.
Publication
Dynamic protein-protein interaction wiring of the human spliceosome.
More than 200 proteins copurify with spliceosomes, the compositionally dynamic RNPs catalyzing pre-mRNA splicing. To better understand protein - protein interactions governing splicing, we systematically investigated interactions between human spliceosomal proteins. A comprehensive Y2H interaction matrix screen generated a protein interaction map comprising 632 interactions between 196 proteins. Among these, 242 interactions were found between spliceosomal core proteins and largely ... [more]
Throughput
- High Throughput
Related interactions
Interaction | Experimental Evidence Code | Dataset | Throughput | Score | Curated By | Notes |
---|---|---|---|---|---|---|
SNRPD3 LSM7 | Co-fractionation Co-fractionation Interaction inferred from the presence of two or more protein subunits in a partially purified protein preparation. If co-fractionation is demonstrated between 3 or more proteins, then add them as a complex. | High | 0.3058 | BioGRID | 1264244 | |
SNRPD3 LSM7 | Two-hybrid Two-hybrid Bait protein expressed as a DNA binding domain (DBD) fusion and prey expressed as a transcriptional activation domain (TAD) fusion and interaction measured by reporter gene activation. | High | - | BioGRID | - | |
LSM7 SNRPD3 | Two-hybrid Two-hybrid Bait protein expressed as a DNA binding domain (DBD) fusion and prey expressed as a transcriptional activation domain (TAD) fusion and interaction measured by reporter gene activation. | High | - | BioGRID | - | |
LSM7 SNRPD3 | Two-hybrid Two-hybrid Bait protein expressed as a DNA binding domain (DBD) fusion and prey expressed as a transcriptional activation domain (TAD) fusion and interaction measured by reporter gene activation. | High | - | BioGRID | - |
Curated By
- BioGRID