BAIT
CASKIN1
CASK interacting protein 1
GO Process (1)
GO Function (2)
GO Component (1)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Rattus norvegicus
PREY
NRXN2
neurexin 2
GO Process (12)
GO Function (3)
GO Component (0)
Gene Ontology Biological Process
- adult behavior [IMP]
- gephyrin clustering [ISS]
- neuroligin clustering [ISS]
- neuron cell-cell adhesion [TAS]
- neurotransmitter secretion [ISS]
- postsynaptic density protein 95 clustering [ISS]
- postsynaptic membrane assembly [ISS]
- social behavior [IMP]
- synapse assembly [ISS]
- synaptic transmission [ISS]
- vocal learning [IMP]
- vocalization behavior [IMP]
Gene Ontology Molecular Function
Homo sapiens
Two-hybrid
Bait protein expressed as a DNA binding domain (DBD) fusion and prey expressed as a transcriptional activation domain (TAD) fusion and interaction measured by reporter gene activation.
Publication
High levels of structural disorder in scaffold proteins as exemplified by a novel neuronal protein, CASK-interactive protein1.
CASK-interactive protein1 is a newly recognized post-synaptic density protein in mammalian neurons. Although its N-terminal region contains several well-known functional domains, its entire C-terminal proline-rich region of 800 amino acids lacks detectable sequence homology to any previously characterized protein. We used multiple techniques for the structural characterization of this region and its three fragments. By bioinformatics predictions, CD spectroscopy, wide-line ... [more]
FEBS J. Jul. 01, 2009; 276(14);3744-56 [Pubmed: 19523119]
Throughput
- Low Throughput
Curated By
- BioGRID