BAIT

GRASP

GRP1 (general receptor for phosphoinositides 1)-associated scaffold protein
GO Process (2)
GO Function (4)
GO Component (1)

Gene Ontology Biological Process

Gene Ontology Cellular Component

Rattus norvegicus

Two-hybrid

Bait protein expressed as a DNA binding domain (DBD) fusion and prey expressed as a transcriptional activation domain (TAD) fusion and interaction measured by reporter gene activation.

Publication

Tamalin is a scaffold protein that interacts with multiple neuronal proteins in distinct modes of protein-protein association.

Kitano J, Yamazaki Y, Kimura K, Masukado T, Nakajima Y, Nakanishi S

Tamalin is a scaffold protein that comprises multiple protein-interacting domains, including a 95-kDa postsynaptic density protein (PSD-95)/discs-large/ZO-1 (PDZ) domain, a leucine-zipper region, and a carboxyl-terminal PDZ binding motif. Tamalin forms a complex with metabotropic glutamate receptors and guanine nucleotide exchange factor cytohesins and promotes intracellular trafficking and cell surface expression of group 1 metabotropic glutamate receptors. In the present study, ... [more]

J. Biol. Chem. Apr. 25, 2003; 278(17);14762-8 [Pubmed: 12586822]

Throughput

  • Low Throughput

Curated By

  • BioGRID