PREY
WWP1
AIP5, Tiul1, hSDRP1
WW domain containing E3 ubiquitin protein ligase 1
GO Process (8)
GO Function (2)
GO Component (5)
Gene Ontology Biological Process
- central nervous system development [NAS]
- ion transmembrane transport [TAS]
- negative regulation of transcription, DNA-templated [ISS]
- protein ubiquitination [TAS]
- protein ubiquitination involved in ubiquitin-dependent protein catabolic process [IBA]
- signal transduction [NAS]
- transmembrane transport [TAS]
- viral entry into host cell [TAS]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
Two-hybrid
Bait protein expressed as a DNA binding domain (DBD) fusion and prey expressed as a transcriptional activation domain (TAD) fusion and interaction measured by reporter gene activation.
Publication
Functional proteomics mapping of a human signaling pathway.
Access to the human genome facilitates extensive functional proteomics studies. Here, we present an integrated approach combining large-scale protein interaction mapping, exploration of the interaction network, and cellular functional assays performed on newly identified proteins involved in a human signaling pathway. As a proof of principle, we studied the Smad signaling system, which is regulated by members of the transforming ... [more]
Genome Res. Jul. 01, 2004; 14(7);1324-32 [Pubmed: 15231748]
Throughput
- High Throughput
Curated By
- BioGRID