BAIT
ZNF512B
GM632
zinc finger protein 512B
GO Process (0)
GO Function (0)
GO Component (0)
Homo sapiens
PREY
AP1G1
ADTG, CLAPG1
adaptor-related protein complex 1, gamma 1 subunit
GO Process (10)
GO Function (5)
GO Component (13)
Gene Ontology Biological Process
- Golgi to lysosome transport [IMP]
- antigen processing and presentation of exogenous peptide antigen via MHC class II [TAS]
- endosome to melanosome transport [IMP]
- melanosome organization [IC]
- membrane organization [TAS]
- positive regulation of natural killer cell degranulation [IMP]
- positive regulation of natural killer cell mediated cytotoxicity [IMP]
- post-Golgi vesicle-mediated transport [TAS]
- regulation of defense response to virus by virus [TAS]
- viral process [TAS]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
- AP-type membrane coat adaptor complex [TAS]
- Golgi apparatus [IDA]
- Golgi membrane [TAS]
- clathrin-coated vesicle [IDA]
- clathrin-coated vesicle membrane [ISS]
- cytoplasm [IDA]
- cytoplasmic vesicle membrane [TAS]
- cytosol [TAS]
- intracellular membrane-bounded organelle [IDA]
- lysosomal membrane [TAS]
- membrane [IDA]
- recycling endosome [IDA]
- trans-Golgi network membrane [TAS]
Homo sapiens
Two-hybrid
Bait protein expressed as a DNA binding domain (DBD) fusion and prey expressed as a transcriptional activation domain (TAD) fusion and interaction measured by reporter gene activation.
Publication
Functional proteomics mapping of a human signaling pathway.
Access to the human genome facilitates extensive functional proteomics studies. Here, we present an integrated approach combining large-scale protein interaction mapping, exploration of the interaction network, and cellular functional assays performed on newly identified proteins involved in a human signaling pathway. As a proof of principle, we studied the Smad signaling system, which is regulated by members of the transforming ... [more]
Genome Res. Jul. 01, 2004; 14(7);1324-32 [Pubmed: 15231748]
Throughput
- High Throughput
Curated By
- BioGRID