BAIT
HIPK3
DYRK6, FIST3, PKY, YAK1, RP1-8L15.1
homeodomain interacting protein kinase 3
GO Process (6)
GO Function (2)
GO Component (2)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Homo sapiens
PREY
C1QA
complement component 1, q subcomponent, A chain
GO Process (4)
GO Function (1)
GO Component (3)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
Two-hybrid
Bait protein expressed as a DNA binding domain (DBD) fusion and prey expressed as a transcriptional activation domain (TAD) fusion and interaction measured by reporter gene activation.
Publication
Functional proteomics mapping of a human signaling pathway.
Access to the human genome facilitates extensive functional proteomics studies. Here, we present an integrated approach combining large-scale protein interaction mapping, exploration of the interaction network, and cellular functional assays performed on newly identified proteins involved in a human signaling pathway. As a proof of principle, we studied the Smad signaling system, which is regulated by members of the transforming ... [more]
Genome Res. Jul. 01, 2004; 14(7);1324-32 [Pubmed: 15231748]
Throughput
- High Throughput
Curated By
- BioGRID