BAIT
YWHAZ
1110013I11Rik, 14-3-3zeta, AI596267, AL022924, AU020854
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide
GO Process (7)
GO Function (7)
GO Component (11)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Mus musculus
PREY
GFAP
AI836096
glial fibrillary acidic protein
GO Process (12)
GO Function (5)
GO Component (9)
Gene Ontology Biological Process
- Bergmann glial cell differentiation [IMP]
- astrocyte development [IGI]
- extracellular matrix organization [IMP]
- intermediate filament organization [IGI, IMP]
- intermediate filament-based process [IMP]
- long-term synaptic potentiation [IMP]
- negative regulation of neuron projection development [IGI, IMP]
- neuron projection regeneration [IMP]
- positive regulation of Schwann cell proliferation [IMP]
- positive regulation of glial cell proliferation [ISO]
- regulation of neurotransmitter uptake [IMP]
- response to wounding [ISO]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Mus musculus
Affinity Capture-MS
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.
Publication
Transgenic mouse proteomics identifies new 14-3-3-associated proteins involved in cytoskeletal rearrangements and cell signaling.
Identification of protein-protein interactions is crucial for unraveling cellular processes and biochemical mechanisms of signal transduction. Here we describe, for the first time, the application of the tandem affinity purification (TAP) and LC-MS method to the characterization of protein complexes from transgenic mice. The TAP strategy developed in transgenic mice allows the emplacement of complexes in their physiological environment in ... [more]
Mol. Cell Proteomics Dec. 01, 2006; 5(12);2211-27 [Pubmed: 16959763]
Throughput
- High Throughput
Curated By
- BioGRID