HIST3H3
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
TAF7
Gene Ontology Biological Process
- DNA-templated transcription, initiation [IDA]
- negative regulation of histone acetylation [IDA]
- negative regulation of protein kinase activity [IDA]
- negative regulation of transcription from RNA polymerase II promoter [IDA]
- negative regulation of transcription, DNA-templated [IDA]
- positive regulation of transcription from RNA polymerase II promoter [IDA]
- spermine transport [ISS]
- transcription from RNA polymerase II promoter [IDA]
- transcription initiation from RNA polymerase II promoter [IDA]
Gene Ontology Molecular Function- histone acetyltransferase binding [IPI]
- protein binding [IPI]
- sequence-specific DNA binding transcription factor activity [IDA]
- thyroid hormone receptor binding [IPI]
- transcription coactivator activity [IDA]
- transcription factor binding [IPI]
- transcription regulatory region DNA binding [IDA]
- vitamin D receptor binding [IPI]
- histone acetyltransferase binding [IPI]
- protein binding [IPI]
- sequence-specific DNA binding transcription factor activity [IDA]
- thyroid hormone receptor binding [IPI]
- transcription coactivator activity [IDA]
- transcription factor binding [IPI]
- transcription regulatory region DNA binding [IDA]
- vitamin D receptor binding [IPI]
Gene Ontology Cellular Component
Affinity Capture-MS
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.
Publication
Selective anchoring of TFIID to nucleosomes by trimethylation of histone H3 lysine 4.
Trimethylation of histone H3 at lysine 4 (H3K4me3) is regarded as a hallmark of active human promoters, but it remains unclear how this posttranslational modification links to transcriptional activation. Using a stable isotope labeling by amino acids in cell culture (SILAC)-based proteomic screening we show that the basal transcription factor TFIID directly binds to the H3K4me3 mark via the plant ... [more]
Throughput
- Low Throughput
Additional Notes
- H3K4me3
Related interactions
| Interaction | Experimental Evidence Code | Dataset | Throughput | Score | Curated By | Notes |
|---|---|---|---|---|---|---|
| HIST3H3 TAF7 | Protein-peptide Protein-peptide An interaction is detected between a protein and a peptide derived from an interaction partner. This includes phage display experiments. | High | - | BioGRID | 1056631 |
Curated By
- BioGRID