BAIT

SYNCRIP

GRY-RBP, GRYRBP, HNRNPQ, HNRPQ1, NSAP1, PP68, hnRNP-Q, RP1-3J17.2
synaptotagmin binding, cytoplasmic RNA interacting protein
Autism spectrum disorder (ASD) Project
Homo sapiens
PREY

IL7R

CD127, CDW127, IL-7R-alpha, IL7RA, ILRA
interleukin 7 receptor
Synthetic Protein Interaction Project
GO Process (5)
GO Function (3)
GO Component (1)

Gene Ontology Biological Process

Gene Ontology Molecular Function

Gene Ontology Cellular Component

Homo sapiens

Protein-RNA

An interaction is detected between and protein and an RNA in vitro.

Publication

Cleavage and polyadenylation specificity factor 1 (CPSF1) regulates alternative splicing of interleukin 7 receptor (IL7R) exon 6.

Evsyukova I, Bradrick SS, Gregory SG, Garcia-Blanco MA

Interleukin 7 receptor, IL7R, is expressed exclusively on cells of the lymphoid lineage, and its expression is crucial for the development and maintenance of T cells. Alternative splicing of IL7R exon 6 results in membrane-bound (exon 6 included) and soluble (exon 6 skipped) IL7R isoforms. Interestingly, the inclusion of exon 6 is affected by a single-nucleotide polymorphism associated with the ... [more]

RNA Jan. 01, 2013; 19(1);103-15 [Pubmed: 23151878]

Throughput

  • Low Throughput

Additional Notes

  • proteins identified by tobramycin RNA affinity chromatography with an IL7R mRNA spanning the first 40 nt of exon 6

Curated By

  • BioGRID