BAIT
PURA
PUR-ALPHA, PUR1, PURALPHA, hCG_45299
purine-rich element binding protein A
GO Process (4)
GO Function (6)
GO Component (3)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
PREY
IL7R
CD127, CDW127, IL-7R-alpha, IL7RA, ILRA
interleukin 7 receptor
GO Process (5)
GO Function (3)
GO Component (1)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
Protein-RNA
An interaction is detected between and protein and an RNA in vitro.
Publication
Cleavage and polyadenylation specificity factor 1 (CPSF1) regulates alternative splicing of interleukin 7 receptor (IL7R) exon 6.
Interleukin 7 receptor, IL7R, is expressed exclusively on cells of the lymphoid lineage, and its expression is crucial for the development and maintenance of T cells. Alternative splicing of IL7R exon 6 results in membrane-bound (exon 6 included) and soluble (exon 6 skipped) IL7R isoforms. Interestingly, the inclusion of exon 6 is affected by a single-nucleotide polymorphism associated with the ... [more]
RNA Jan. 01, 2013; 19(1);103-15 [Pubmed: 23151878]
Throughput
- Low Throughput
Additional Notes
- proteins identified by tobramycin RNA affinity chromatography with an IL7R mRNA spanning the first 40 nt of exon 6
Curated By
- BioGRID