NCF1
Gene Ontology Biological Process
- antigen processing and presentation of exogenous peptide antigen via MHC class I [TAS]
- antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [TAS]
- antigen processing and presentation of peptide antigen via MHC class I [TAS]
- innate immune response [TAS]
- interaction with host [TAS]
- oxidation-reduction process [IMP]
- phagosome maturation [TAS]
- protein targeting to membrane [IDA]
- respiratory burst [TAS]
- superoxide anion generation [IMP, TAS]
- superoxide metabolic process [TAS]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
CTTN
Gene Ontology Biological Process
- actin cytoskeleton reorganization [ISS]
- cell motility [ISS]
- focal adhesion assembly [ISS]
- intracellular protein transport [IMP]
- lamellipodium organization [ISS]
- neuron projection morphogenesis [ISS]
- positive regulation of actin filament polymerization [ISS]
- receptor-mediated endocytosis [ISS]
- regulation of axon extension [ISS]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Affinity Capture-Western
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner identified by Western blot with a specific polyclonal antibody or second epitope tag. This category is also used if an interacting protein is visualized directly by dye stain or radioactivity. Note that this differs from any co-purification experiment involving affinity capture in that the co-purification experiment involves at least one extra purification step to get rid of potential contaminating proteins.
Publication
p47phox associates with the cytoskeleton through cortactin in human vascular smooth muscle cells: role in NAD(P)H oxidase regulation by angiotensin II.
We tested the hypothesis that p47phox associates with the actin cytoskeleton, enabling site-directed activation of NAD(P)H oxidase, and assessed whether these actions influence reactive oxygen species (ROS) generation and signaling by angiotensin II (Ang II) in vascular smooth muscle cells (VSMCs) from human resistance and coronary arteries.Electroporation of anti-p47phox antibody into VSMCs abrogated Ang II-mediated O2 generation, establishing the requirement ... [more]
Throughput
- Low Throughput
Curated By
- BioGRID