BAIT

KIDINS220B

dZ119J18.2, fj35h03, kidins220, wu:fj35h03, zgc:63531, DKEYP-7F8.3
kinase D-interacting substrate 220b
GO Process (0)
GO Function (1)
GO Component (1)

Gene Ontology Molecular Function

Gene Ontology Cellular Component

Danio rerio
PREY

LOC100149029

pdzrn3
E3 ubiquitin-protein ligase PDZRN3
GO Process (0)
GO Function (0)
GO Component (0)
Danio rerio

Affinity Capture-Western

An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner identified by Western blot with a specific polyclonal antibody or second epitope tag. This category is also used if an interacting protein is visualized directly by dye stain or radioactivity. Note that this differs from any co-purification experiment involving affinity capture in that the co-purification experiment involves at least one extra purification step to get rid of potential contaminating proteins.

Publication

Kidins220/ARMS interacts with Pdzrn3, a protein containing multiple binding domains.

Andreazzoli M, Gestri G, Landi E, D'Orsi B, Barilari M, Iervolino A, Vitiello M, Wilson SW, Dente L

We report the identification of a novel partner of Kidins220/ARMS (Kinase D-interacting substrate of 220 kDa/Ankyrin Repeat-rich Membrane Spanning) an adaptor of neurotrophin receptors playing crucial roles during neurogenesis. Screening a phage display library of brain cDNA products we found that D. rerio Pdzrn3, a protein containing RING-finger and PDZ-domains, interacts with Kidins220/ARMS through its first PDZ-domain. Both zebrafish proteins share high ... [more]

Biochimie Sep. 01, 2012; 94(9);2054-7 [Pubmed: 22609016]

Throughput

  • Low Throughput

Related interactions

InteractionExperimental Evidence CodeDatasetThroughputScoreCurated ByNotes
LOC100149029 KIDINS220B
Affinity Capture-Western
Affinity Capture-Western

An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner identified by Western blot with a specific polyclonal antibody or second epitope tag. This category is also used if an interacting protein is visualized directly by dye stain or radioactivity. Note that this differs from any co-purification experiment involving affinity capture in that the co-purification experiment involves at least one extra purification step to get rid of potential contaminating proteins.

Low-BioGRID
-

Curated By

  • BioGRID