BAIT

MBP

C76307, Hmbpr, R75289, golli-mbp, mld, shi
myelin basic protein
GO Process (3)
GO Function (1)
GO Component (5)

Gene Ontology Biological Process

Gene Ontology Molecular Function

Gene Ontology Cellular Component

Mus musculus
PREY

MPP2

DLG2
membrane protein, palmitoylated 2 (MAGUK p55 subfamily member 2)
GO Process (2)
GO Function (1)
GO Component (2)

Gene Ontology Biological Process

Gene Ontology Molecular Function

Gene Ontology Cellular Component

Homo sapiens

Protein-peptide

An interaction is detected between a protein and a peptide derived from an interaction partner. This includes phage display experiments.

Publication

Binding of the proline-rich segment of myelin basic protein to SH3 domains: spectroscopic, microarray, and modeling studies of ligand conformation and effects of posttranslational modifications.

Polverini E, Rangaraj G, Libich DS, Boggs JM, Harauz G

Myelin basic protein (MBP) is a multifunctional protein involved in maintaining the stability and integrity of the myelin sheath by a variety of interactions with membranes and with cytoskeletal and other proteins. A central segment of MBP is highly conserved in mammals and consists of a membrane surface-associated amphipathic alpha-helix, immediately followed by a proline-rich segment that we hypothesize is ... [more]

Biochemistry Jan. 08, 2008; 47(1);267-82 [Pubmed: 18067320]

Throughput

  • Low Throughput

Additional Notes

  • recombinant murine MBP binds to the SH3 domain on a peptide array

Curated By

  • BioGRID