BAIT
FES
FPS
FES proto-oncogene, tyrosine kinase
GO Process (22)
GO Function (5)
GO Component (6)
Gene Ontology Biological Process
- axon guidance [TAS]
- cell migration [IBA]
- cell proliferation [TAS]
- chemotaxis [IBA]
- epidermal growth factor receptor signaling pathway [IBA]
- innate immune response [IBA]
- multicellular organismal development [TAS]
- peptidyl-tyrosine autophosphorylation [IBA]
- peptidyl-tyrosine phosphorylation [IDA]
- positive regulation of actin cytoskeleton reorganization [IMP]
- positive regulation of microtubule polymerization [IMP]
- positive regulation of myeloid cell differentiation [IMP]
- positive regulation of neuron projection development [IMP]
- protein autophosphorylation [IDA]
- protein phosphorylation [TAS]
- regulation of cell adhesion [IMP]
- regulation of cell differentiation [IMP]
- regulation of cell motility [IMP]
- regulation of cell proliferation [IMP]
- regulation of cell shape [IMP]
- regulation of mast cell degranulation [IMP]
- regulation of vesicle-mediated transport [TAS]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
PREY
MDFI
I-MF, I-mfa, RP4-696P19.1
MyoD family inhibitor
GO Process (6)
GO Function (1)
GO Component (1)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Homo sapiens
Two-hybrid
Bait protein expressed as a DNA binding domain (DBD) fusion and prey expressed as a transcriptional activation domain (TAD) fusion and interaction measured by reporter gene activation.
Publication
An empirical framework for binary interactome mapping.
Several attempts have been made to systematically map protein-protein interaction, or 'interactome', networks. However, it remains difficult to assess the quality and coverage of existing data sets. Here we describe a framework that uses an empirically-based approach to rigorously dissect quality parameters of currently available human interactome maps. Our results indicate that high-throughput yeast two-hybrid (HT-Y2H) interactions for human proteins ... [more]
Nat. Methods Jan. 01, 2009; 6(1);83-90 [Pubmed: 19060904]
Throughput
- High Throughput
Additional Notes
- Human proteins expressed in S. cerevisiae
Curated By
- BioGRID