STX4A
Gene Ontology Biological Process
- SNARE complex assembly [IDA]
- intracellular protein transport [IBA]
- long-term synaptic potentiation [ISO]
- membrane fusion [ISO]
- organelle fusion [ISO]
- positive regulation of catalytic activity [ISO]
- positive regulation of cell adhesion [ISO]
- positive regulation of cell migration [ISO]
- positive regulation of cell proliferation [ISO]
- positive regulation of chemotaxis [ISO]
- positive regulation of eosinophil degranulation [ISO]
- positive regulation of establishment of protein localization to plasma membrane [ISO]
- positive regulation of immunoglobulin secretion [ISO]
- positive regulation of insulin secretion involved in cellular response to glucose stimulus [ISO]
- positive regulation of protein localization to cell surface [ISO]
- positive regulation of protein localization to plasma membrane [ISO]
- protein complex assembly [ISO]
- regulation of exocytosis [ISO]
- regulation of extrinsic apoptotic signaling pathway via death domain receptors [ISO]
- response to hydroperoxide [ISO]
- synaptic vesicle docking [ISO]
- synaptic vesicle exocytosis [TAS]
- synaptic vesicle fusion to presynaptic membrane [IBA]
- vesicle docking [IBA]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
- SNARE complex [IBA, ISO]
- apical plasma membrane [ISO]
- basolateral plasma membrane [IDA, ISO]
- cell [TAS]
- cell surface [IDA, ISO]
- cytoplasm [IDA]
- dendritic spine [ISO]
- endosome [ISO]
- extracellular space [ISO]
- extracellular vesicular exosome [ISO]
- integral component of membrane [IBA]
- intracellular [ISO]
- lamellipodium [ISO]
- lateral loop [IDA]
- membrane [ISO]
- myelin sheath adaxonal region [IDA]
- perinuclear region of cytoplasm [IDA]
- plasma membrane [IDA, ISO]
- sarcolemma [ISO]
- somatodendritic compartment [ISO]
- specific granule [ISO]
- synapse [ISO]
- synaptic vesicle [IBA]
- trans-Golgi network [IDA]
STXBP3A
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Affinity Capture-Western
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner identified by Western blot with a specific polyclonal antibody or second epitope tag. This category is also used if an interacting protein is visualized directly by dye stain or radioactivity. Note that this differs from any co-purification experiment involving affinity capture in that the co-purification experiment involves at least one extra purification step to get rid of potential contaminating proteins.
Publication
Adipocytes from Munc18c-null mice show increased sensitivity to insulin-stimulated GLUT4 externalization.
Insulin-stimulated glucose uptake in adipocytes is mediated by translocation of vesicles containing the glucose transporter GLUT4 from intracellular storage sites to the cell periphery and the subsequent fusion of these vesicles with the plasma membrane, resulting in the externalization of GLUT4. Fusion of the GLUT4-containing vesicles with the plasma membrane is mediated by a soluble N-ethylmaleimide-sensitive factor attachment protein receptor ... [more]
Throughput
- Low Throughput
Related interactions
| Interaction | Experimental Evidence Code | Dataset | Throughput | Score | Curated By | Notes |
|---|---|---|---|---|---|---|
| STXBP3A STX4A | Affinity Capture-Western Affinity Capture-Western An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner identified by Western blot with a specific polyclonal antibody or second epitope tag. This category is also used if an interacting protein is visualized directly by dye stain or radioactivity. Note that this differs from any co-purification experiment involving affinity capture in that the co-purification experiment involves at least one extra purification step to get rid of potential contaminating proteins. | Low | - | BioGRID | - |
Curated By
- BioGRID