ATP6V0A4
Gene Ontology Biological Process
- ATP catabolic process [IBA]
- ATP hydrolysis coupled proton transport [IPI, ISA]
- ATP synthesis coupled proton transport [IBA]
- excretion [ISO]
- ossification [ISO]
- proton transport [ISO]
- regulation of pH [ISO]
- sensory perception of sound [ISO]
- vacuolar acidification [IBA]
- vacuolar proton-transporting V-type ATPase complex assembly [IBA]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
- apical part of cell [IDA, ISO]
- apical plasma membrane [IDA, ISO]
- brush border [IDA]
- brush border membrane [ISO]
- cell [IBA]
- endosome [IDA]
- extracellular vesicular exosome [ISO]
- intracellular [IBA]
- lysosomal membrane [ISO]
- plasma membrane [ISO]
- vacuolar proton-transporting V-type ATPase complex [IPI, ISA, ISO]
- vacuole [IBA]
ATP6V0D2
Gene Ontology Cellular Component
Affinity Capture-Western
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner identified by Western blot with a specific polyclonal antibody or second epitope tag. This category is also used if an interacting protein is visualized directly by dye stain or radioactivity. Note that this differs from any co-purification experiment involving affinity capture in that the co-purification experiment involves at least one extra purification step to get rid of potential contaminating proteins.
Publication
a4, a unique kidney-specific isoform of mouse vacuolar H+-ATPase subunit a.
The vacuolar-type H+ -ATPase (V-ATPase) translocates protons across membranes. Here, we have identified a mouse cDNA coding for a fourth isoform (a4) of the membrane sector subunit a of V-ATPase. This isoform was specifically expressed in kidney, but not in the heart, brain, spleen, lung, liver, muscle, or testis. Immunoprecipitation experiments, together with sequence similarities for other isoforms (a1, a2, ... [more]
Throughput
- Low Throughput
Curated By
- BioGRID