BAIT
FGF2
Fgf-2, Fgfb, bFGF, DN-452A22.6
fibroblast growth factor 2
GO Process (51)
GO Function (6)
GO Component (4)
Gene Ontology Biological Process
- activation of MAPKK activity [IDA]
- angiogenesis [IDA, IGI]
- angiogenesis involved in coronary vascular morphogenesis [ISO]
- branching involved in ureteric bud morphogenesis [ISO]
- cardiac muscle cell proliferation [TAS]
- cell migration involved in sprouting angiogenesis [ISO]
- chondroblast differentiation [ISO]
- corticotropin hormone secreting cell differentiation [IDA]
- embryo development ending in birth or egg hatching [ISO]
- fibroblast growth factor receptor signaling pathway [IGI, ISO]
- glial cell differentiation [IMP]
- hyaluronan catabolic process [ISO]
- inositol phosphate biosynthetic process [ISO]
- lung development [IDA, IGI]
- mammary gland epithelial cell differentiation [IDA]
- negative regulation of blood vessel endothelial cell migration [ISO]
- negative regulation of cell death [ISO]
- negative regulation of cell proliferation [IGI]
- negative regulation of fibroblast migration [ISO]
- negative regulation of wound healing [ISO]
- organ induction [IDA]
- phosphatidylinositol biosynthetic process [ISO]
- positive chemotaxis [ISO]
- positive regulation of ERK1 and ERK2 cascade [IDA, ISO]
- positive regulation of angiogenesis [IDA, IGI, ISO]
- positive regulation of blood vessel endothelial cell migration [ISO]
- positive regulation of canonical Wnt signaling pathway [IDA]
- positive regulation of cardiac muscle cell proliferation [ISO]
- positive regulation of cell differentiation [IDA]
- positive regulation of cell fate specification [ISO]
- positive regulation of cell proliferation [IDA, IGI, ISO]
- positive regulation of cerebellar granule cell precursor proliferation [IDA]
- positive regulation of endothelial cell migration [IDA]
- positive regulation of endothelial cell proliferation [IDA, ISO]
- positive regulation of epithelial cell proliferation [IDA]
- positive regulation of gene expression [IDA]
- positive regulation of osteoblast differentiation [IGI]
- positive regulation of phosphatidylinositol 3-kinase activity [ISO]
- positive regulation of phospholipase C activity [ISO]
- positive regulation of protein kinase B signaling [IDA]
- positive regulation of protein phosphorylation [IDA]
- positive regulation of smooth muscle cell proliferation [ISO]
- positive regulation of transcription from RNA polymerase II promoter [IDA, IGI, ISO]
- positive regulation of transcription, DNA-templated [ISO, TAS]
- regulation of cell cycle [IDA]
- regulation of retinal cell programmed cell death [IDA]
- release of sequestered calcium ion into cytosol [ISO]
- response to axon injury [IMP]
- stem cell development [IMP]
- substantia nigra development [IMP]
- thyroid-stimulating hormone-secreting cell differentiation [IDA]
Gene Ontology Molecular Function
Mus musculus
PREY
FGFR2
AU043015, AW556123, Bek, Fgfr-2, Fgfr-7, Fgfr7, KGFR, KGFRTr, svs
fibroblast growth factor receptor 2
GO Process (102)
GO Function (4)
GO Component (11)
Gene Ontology Biological Process
- angiogenesis [IGI]
- axonogenesis [IMP]
- bone development [IMP]
- bone mineralization [IMP]
- bone morphogenesis [IMP]
- branch elongation involved in salivary gland morphogenesis [IGI, IMP]
- branching involved in labyrinthine layer morphogenesis [IMP]
- branching involved in prostate gland morphogenesis [IMP]
- branching involved in salivary gland morphogenesis [IMP]
- branching morphogenesis of a nerve [IMP]
- bud elongation involved in lung branching [IMP]
- cell fate commitment [IDA]
- cell-cell signaling [IMP]
- coronal suture morphogenesis [IMP]
- digestive tract development [IMP]
- embryonic cranial skeleton morphogenesis [ISO]
- embryonic digestive tract morphogenesis [IMP]
- embryonic organ development [IMP]
- embryonic organ morphogenesis [IMP]
- embryonic pattern specification [IMP]
- endodermal digestive tract morphogenesis [IMP]
- epidermis morphogenesis [IMP]
- epithelial cell differentiation [IMP]
- epithelial cell proliferation [IMP]
- epithelial cell proliferation involved in salivary gland morphogenesis [IGI, IMP]
- epithelial to mesenchymal transition [ISO]
- epithelial tube branching involved in lung morphogenesis [IMP]
- fibroblast growth factor receptor signaling pathway [IGI, IMP, ISO]
- fibroblast growth factor receptor signaling pathway involved in hemopoiesis [IMP]
- fibroblast growth factor receptor signaling pathway involved in mammary gland specification [IMP]
- fibroblast growth factor receptor signaling pathway involved in negative regulation of apoptotic process in bone marrow [IMP]
- fibroblast growth factor receptor signaling pathway involved in orbitofrontal cortex development [IMP]
- fibroblast growth factor receptor signaling pathway involved in positive regulation of cell proliferation in bone marrow [IMP]
- gland morphogenesis [IMP]
- hair follicle morphogenesis [IMP]
- in utero embryonic development [IGI, IMP]
- inner ear morphogenesis [IMP]
- lacrimal gland development [IMP]
- lateral sprouting from an epithelium [IMP]
- lens fiber cell development [IGI, IMP]
- limb bud formation [IMP]
- lung alveolus development [IGI, IMP]
- lung development [IGI, IMP]
- lung lobe morphogenesis [IMP]
- lung-associated mesenchyme development [IGI, IMP]
- mammary gland bud formation [IMP]
- membranous septum morphogenesis [IMP]
- mesenchymal cell differentiation [IGI]
- mesenchymal cell differentiation involved in lung development [IGI]
- mesenchymal cell proliferation involved in lung development [IMP]
- midbrain development [IGI]
- morphogenesis of embryonic epithelium [IMP]
- multicellular organism growth [IMP]
- negative regulation of cell proliferation [IGI]
- negative regulation of epithelial cell proliferation [ISO]
- negative regulation of mitosis [IGI]
- negative regulation of transcription from RNA polymerase II promoter [IMP]
- neuromuscular junction development [IMP]
- odontogenesis [IMP]
- orbitofrontal cortex development [IMP]
- organ growth [IMP]
- organ morphogenesis [IMP]
- otic vesicle formation [IMP]
- outflow tract septum morphogenesis [IMP]
- peptidyl-tyrosine phosphorylation [ISO]
- positive regulation of ERK1 and ERK2 cascade [IGI]
- positive regulation of MAPK cascade [ISO]
- positive regulation of Wnt signaling pathway [IMP]
- positive regulation of canonical Wnt signaling pathway [IGI, IMP]
- positive regulation of cardiac muscle cell proliferation [IGI]
- positive regulation of cell cycle [IMP]
- positive regulation of cell division [IMP]
- positive regulation of cell proliferation [IGI, IMP, ISO]
- positive regulation of epithelial cell proliferation [IGI]
- positive regulation of epithelial cell proliferation involved in lung morphogenesis [IMP]
- positive regulation of mesenchymal cell proliferation [IGI]
- positive regulation of phospholipase activity [ISO]
- positive regulation of smooth muscle cell proliferation [ISO]
- positive regulation of transcription from RNA polymerase II promoter [IMP]
- post-embryonic development [IMP]
- prostate epithelial cord arborization involved in prostate glandular acinus morphogenesis [IMP]
- prostate epithelial cord elongation [IMP]
- prostate gland morphogenesis [IMP]
- protein autophosphorylation [ISO]
- pyramidal neuron development [IMP]
- regulation of ERK1 and ERK2 cascade [IMP]
- regulation of branching involved in prostate gland morphogenesis [IMP]
- regulation of cell fate commitment [IMP]
- regulation of cell proliferation [IMP]
- regulation of epithelial cell proliferation [IMP]
- regulation of fibroblast growth factor receptor signaling pathway [IMP]
- regulation of morphogenesis of a branching structure [IMP]
- regulation of multicellular organism growth [IMP]
- regulation of smooth muscle cell differentiation [IMP]
- regulation of smoothened signaling pathway [IMP]
- reproductive structure development [IMP]
- squamous basal epithelial stem cell differentiation involved in prostate gland acinus development [IMP]
- synaptic vesicle transport [IMP]
- ureteric bud development [IGI]
- vasculogenesis involved in coronary vascular morphogenesis [TAS]
- ventricular cardiac muscle tissue morphogenesis [IMP]
- ventricular zone neuroblast division [IMP]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Mus musculus
Reconstituted Complex
An interaction is detected between purified proteins in vitro.
Publication
Identification of a new fibroblast growth factor receptor, FGFR5.
A novel fibroblast growth factor receptor (FGFR), designated FGFR5, was identified from an EST database of a murine lymph node stromal cell cDNA library. The EST has approximately 32% identity to the extracellular domain of FGFR1-4. Library screening with this EST identified two full-length alternative transcripts which we designated as FGFR5 beta and FGFR5 gamma. The main difference between these ... [more]
Gene Jun. 27, 2001; 271(2);171-82 [Pubmed: 11418238]
Throughput
- Low Throughput
Curated By
- BioGRID