BAIT

CBX8

PC3, RC1
chromobox homolog 8
GO Process (1)
GO Function (2)
GO Component (5)
Homo sapiens

Affinity Capture-MS

An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.

Publication

Interaction proteomics analysis of polycomb proteins defines distinct PRC1 complexes in mammalian cells.

Vandamme J, Voelkel P, Rosnoblet C, Le Faou P, Angrand PO

Polycomb group (PcG) proteins maintain transcriptional repression of hundreds of genes involved in development, signaling or cancer using chromatin-based epigenetic mechanisms. Biochemical studies in Drosophila have revealed that PcG proteins associate in at least two classes of protein complexes known as Polycomb repressive complexes 1 and 2 (PRC1 and PRC2). Drosophila core PRC1 is composed of four subunits, Polycomb (Pc), ... [more]

Mol. Cell Proteomics Apr. 01, 2011; 10(4);M110.002642 [Pubmed: 21282530]

Throughput

  • Low Throughput

Curated By

  • BioGRID