BAIT
POP2
CAF1, CCR4-NOT core DEDD family RNase subunit POP2, L000001465, YNR052C
RNase of the DEDD superfamily; subunit of the Ccr4-Not complex that mediates 3' to 5' mRNA deadenylation
GO Process (4)
GO Function (1)
GO Component (4)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Saccharomyces cerevisiae (S288c)
PREY
AAC3
ANC3, ADP/ATP carrier protein AAC3, L000000005, YBR085W
Mitochondrial inner membrane ADP/ATP translocator; exchanges cytosolic ADP for mitochondrially synthesized ATP; expressed under anaerobic conditions; similar to Aac1p; has roles in maintenance of viability and in respiration; AAC3 has a paralog, PET9, that arose from the whole genome duplication
GO Process (3)
GO Function (1)
GO Component (3)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Saccharomyces cerevisiae (S288c)
Synthetic Growth Defect
A genetic interaction is inferred when mutations in separate genes, each of which alone causes a minimal phenotype, result in a significant growth defect under a given condition when combined in the same cell.
Publication
Large-scale investigation of oxygen response mutants in Saccharomyces cerevisiae.
A genome-wide screen of a yeast non-essential gene-deletion library was used to identify sick phenotypes due to oxygen deprivation. The screen provided a manageable list of 384 potentially novel as well as known oxygen responding (anoxia-survival) genes. The gene-deletion mutants were further assayed for sensitivity to ferrozine and cobalt to obtain a subset of 34 oxygen-responsive candidate genes including the ... [more]
Mol Biosyst Mar. 07, 2013; 0(0); [Pubmed: 23467670]
Throughput
- High Throughput|Low Throughput
Ontology Terms
- phenotype: vegetative growth (APO:0000106)
- phenotype: colony size (APO:0000063)
Additional Notes
- High Throughput: SGA analysis
- Low Throughput: random spore analysis to confirm HTP result
Curated By
- BioGRID