BAIT
UBC
ubiquitin C
GO Process (2)
GO Function (2)
GO Component (2)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Rattus norvegicus
PREY
DBI
Acbp, Acoabp3, Ep, Odn, RNACOABP3, Ttn
diazepam binding inhibitor (GABA receptor modulator, acyl-CoA binding protein)
GO Process (19)
GO Function (5)
GO Component (10)
Gene Ontology Biological Process
- acyl-CoA metabolic process [TAS]
- behavioral fear response [ISO]
- brain development [IEP]
- cellular response to nutrient [IEP]
- glial cell proliferation [IDA]
- hair follicle development [ISO]
- lateral ventricle development [ISO]
- learning or memory [ISO]
- long-term synaptic potentiation [ISO]
- negative regulation of fatty acid beta-oxidation [IDA]
- pancreatic juice secretion [IEP]
- phosphatidylcholine acyl-chain remodeling [ISO]
- positive regulation of lipid biosynthetic process [IDA]
- positive regulation of release of sequestered calcium ion into cytosol [IMP]
- protein palmitoylation [ISO]
- regulation of synaptic transmission, GABAergic [IDA]
- skin development [ISO]
- steroid biosynthetic process [TAS]
- triglyceride metabolic process [ISO]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Rattus norvegicus
Affinity Capture-MS
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.
Publication
Synaptic Protein Ubiquitination in Rat Brain Revealed by Antibody-based Ubiquitome Analysis.
Protein ubiquitination is an essential post-translational modification regulating neurodevelopment, synaptic plasticity, learning, and memory, and its dysregulation contributes to the pathogenesis of neurological diseases. Here we report a systematic analysis of ubiquitinated proteome (ubiquitome) in rat brain using a newly developed monoclonal antibody that recognizes the diglycine tag on lysine residues in trypsinized peptides (K-GG peptides). Initial antibody specificity analysis ... [more]
J. Proteome Res. Aug. 15, 2012; 0(0); [Pubmed: 22871113]
Throughput
- Low Throughput
Curated By
- BioGRID