BAIT
UBC
ubiquitin C
GO Process (2)
GO Function (2)
GO Component (2)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Rattus norvegicus
PREY
AQP4
AQP-4, MIWC2, Miwc
aquaporin 4
GO Process (24)
GO Function (3)
GO Component (12)
Gene Ontology Biological Process
- carbon dioxide transport [IDA]
- cellular response to estradiol stimulus [IEP]
- cellular response to glucose stimulus [IMP]
- cellular response to interferon-gamma [ISO]
- cellular response to interleukin-1 [IEP]
- cellular response to interleukin-6 [IEP]
- cellular water homeostasis [IBA]
- female pregnancy [IEP]
- glycerol transport [IBA]
- hyperosmotic salinity response [IEP]
- ion transmembrane transport [IBA]
- multicellular organismal water homeostasis [ISO]
- negative regulation of cell adhesion molecule production [IMP]
- negative regulation of interleukin-1 beta production [IMP]
- negative regulation of interleukin-6 production [IMP]
- protein homooligomerization [IDA]
- regulation of vascular endothelial growth factor production [IMP]
- renal water absorption [ISO]
- response to glucocorticoid [IEP]
- response to radiation [IEP]
- sensory perception of sound [ISO]
- transmembrane transport [ISO]
- water homeostasis [ISO]
- water transport [IDA, ISO]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
- T-tubule [IDA]
- basal plasma membrane [IDA]
- basolateral plasma membrane [IDA, ISO]
- cell projection membrane [IDA]
- cell-cell junction [ISO]
- cytoplasm [ISO]
- external side of plasma membrane [ISO]
- integral component of plasma membrane [IDA]
- membrane [IDA]
- plasma membrane [ISO]
- protein complex [IDA]
- sarcolemma [IDA]
Rattus norvegicus
Affinity Capture-MS
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.
Publication
Synaptic Protein Ubiquitination in Rat Brain Revealed by Antibody-based Ubiquitome Analysis.
Protein ubiquitination is an essential post-translational modification regulating neurodevelopment, synaptic plasticity, learning, and memory, and its dysregulation contributes to the pathogenesis of neurological diseases. Here we report a systematic analysis of ubiquitinated proteome (ubiquitome) in rat brain using a newly developed monoclonal antibody that recognizes the diglycine tag on lysine residues in trypsinized peptides (K-GG peptides). Initial antibody specificity analysis ... [more]
J. Proteome Res. Aug. 15, 2012; 0(0); [Pubmed: 22871113]
Throughput
- Low Throughput
Curated By
- BioGRID