BAIT
UBC
ubiquitin C
GO Process (2)
GO Function (2)
GO Component (2)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Rattus norvegicus
PREY
ABCG1
Abc8
ATP-binding cassette, subfamily G (WHITE), member 1
GO Process (21)
GO Function (9)
GO Component (8)
Gene Ontology Biological Process
- amyloid precursor protein catabolic process [ISO]
- cholesterol efflux [ISO]
- cholesterol homeostasis [ISO]
- cholesterol metabolic process [ISO]
- cholesterol transport [ISO, TAS]
- glycoprotein transport [ISO]
- high-density lipoprotein particle remodeling [ISO]
- intracellular cholesterol transport [ISO]
- low-density lipoprotein particle remodeling [ISO]
- negative regulation of lipid storage [ISO]
- phospholipid efflux [ISO]
- phospholipid homeostasis [ISO]
- positive regulation of cholesterol biosynthetic process [ISO]
- positive regulation of cholesterol efflux [ISO]
- regulation of cholesterol esterification [ISO]
- regulation of transcription, DNA-templated [ISO]
- response to high density lipoprotein particle [ISO]
- response to lipid [ISO]
- response to organic substance [ISO]
- reverse cholesterol transport [ISO]
- toxin transport [ISO]
Gene Ontology Molecular Function- ADP binding [ISO]
- ATP binding [ISO]
- cholesterol transporter activity [ISO]
- glycoprotein transporter activity [ISO]
- phospholipid transporter activity [ISO]
- protein heterodimerization activity [ISO]
- protein homodimerization activity [ISO]
- sterol-transporting ATPase activity [ISO]
- toxin transporter activity [ISO]
- ADP binding [ISO]
- ATP binding [ISO]
- cholesterol transporter activity [ISO]
- glycoprotein transporter activity [ISO]
- phospholipid transporter activity [ISO]
- protein heterodimerization activity [ISO]
- protein homodimerization activity [ISO]
- sterol-transporting ATPase activity [ISO]
- toxin transporter activity [ISO]
Gene Ontology Cellular Component
Rattus norvegicus
Affinity Capture-MS
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.
Publication
Synaptic Protein Ubiquitination in Rat Brain Revealed by Antibody-based Ubiquitome Analysis.
Protein ubiquitination is an essential post-translational modification regulating neurodevelopment, synaptic plasticity, learning, and memory, and its dysregulation contributes to the pathogenesis of neurological diseases. Here we report a systematic analysis of ubiquitinated proteome (ubiquitome) in rat brain using a newly developed monoclonal antibody that recognizes the diglycine tag on lysine residues in trypsinized peptides (K-GG peptides). Initial antibody specificity analysis ... [more]
J. Proteome Res. Aug. 15, 2012; 0(0); [Pubmed: 22871113]
Throughput
- Low Throughput
Curated By
- BioGRID