BAIT
UBC
ubiquitin C
GO Process (2)
GO Function (2)
GO Component (2)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Rattus norvegicus
PREY
KCNJ10
potassium inwardly-rectifying channel, subfamily J, member 10
GO Process (22)
GO Function (6)
GO Component (6)
Gene Ontology Biological Process
- L-glutamate import [IMP]
- L-glutamate uptake involved in synaptic transmission [ISO]
- adult walking behavior [ISO]
- central nervous system myelination [ISO]
- inflammatory response [IEP]
- membrane hyperpolarization [IMP]
- oligodendrocyte development [ISO]
- optic nerve development [IEP]
- potassium ion homeostasis [ISO]
- potassium ion import [IMP]
- potassium ion transmembrane transport [ISO]
- potassium ion transport [ISO]
- protein homotetramerization [IDA]
- regulation of ion transmembrane transport [IBA, ISO]
- regulation of long-term neuronal synaptic plasticity [ISO]
- regulation of membrane potential [ISO]
- regulation of resting membrane potential [ISO]
- regulation of sensory perception of pain [IMP]
- response to blue light [IEP]
- response to glucocorticoid [IEP]
- response to mineralocorticoid [IEP]
- visual perception [ISO]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Rattus norvegicus
Affinity Capture-MS
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.
Publication
Synaptic Protein Ubiquitination in Rat Brain Revealed by Antibody-based Ubiquitome Analysis.
Protein ubiquitination is an essential post-translational modification regulating neurodevelopment, synaptic plasticity, learning, and memory, and its dysregulation contributes to the pathogenesis of neurological diseases. Here we report a systematic analysis of ubiquitinated proteome (ubiquitome) in rat brain using a newly developed monoclonal antibody that recognizes the diglycine tag on lysine residues in trypsinized peptides (K-GG peptides). Initial antibody specificity analysis ... [more]
J. Proteome Res. Aug. 15, 2012; 0(0); [Pubmed: 22871113]
Throughput
- Low Throughput
Curated By
- BioGRID