BAIT
UBC
ubiquitin C
GO Process (2)
GO Function (2)
GO Component (2)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Rattus norvegicus
PREY
KCNMA1
BKCa, KCNMA1b, KCNMA1c, Kcnma, Slo
potassium large conductance calcium-activated channel, subfamily M, alpha member 1
GO Process (33)
GO Function (8)
GO Component (17)
Gene Ontology Biological Process
- adult walking behavior [ISO]
- auditory receptor cell differentiation [ISO]
- cell maturation [ISO]
- cellular potassium ion homeostasis [ISO]
- circadian rhythm [ISO]
- eye blink reflex [ISO]
- locomotor rhythm [ISO]
- micturition [ISO]
- negative regulation of cell volume [ISO]
- neuromuscular process controlling balance [ISO]
- neuronal action potential [ISO]
- positive regulation of apoptotic process [ISO]
- potassium ion transmembrane transport [IBA, ISO]
- potassium ion transport [ISO]
- protein homooligomerization [ISO]
- protein homotetramerization [IDA]
- regulation of aldosterone metabolic process [ISO]
- regulation of ion transmembrane transport [ISO]
- regulation of membrane potential [ISO]
- regulation of vasodilation [IDA]
- relaxation of vascular smooth muscle [ISO]
- response to calcium ion [IDA, ISO]
- response to carbon monoxide [ISO]
- response to corticosteroid [IDA]
- response to estrogen [IDA]
- response to hypoxia [IDA, ISO]
- response to osmotic stress [ISO]
- response to pH [IDA]
- saliva secretion [ISO]
- sensory perception of sound [ISO]
- smooth muscle contraction involved in micturition [ISO]
- synaptic transmission [ISO]
- vasodilation [ISO]
Gene Ontology Molecular Function- actin binding [ISO]
- calcium-activated potassium channel activity [IDA, ISO]
- large conductance calcium-activated potassium channel activity [IBA, IDA, ISO]
- potassium channel activity [ISO]
- protein binding [IPI]
- protein complex binding [IPI]
- protein homodimerization activity [IDA]
- voltage-gated potassium channel activity [IBA, ISO]
- actin binding [ISO]
- calcium-activated potassium channel activity [IDA, ISO]
- large conductance calcium-activated potassium channel activity [IBA, IDA, ISO]
- potassium channel activity [ISO]
- protein binding [IPI]
- protein complex binding [IPI]
- protein homodimerization activity [IDA]
- voltage-gated potassium channel activity [IBA, ISO]
Gene Ontology Cellular Component
- apical plasma membrane [IBA, ISO]
- caveola [ISO]
- cell [ISO]
- cytoplasm [ISO]
- dendrite [IDA]
- endoplasmic reticulum [ISO]
- external side of plasma membrane [IDA, ISO]
- extracellular vesicular exosome [ISO]
- integral component of membrane [ISO]
- neuronal cell body [IDA]
- perinuclear region of cytoplasm [IDA]
- plasma membrane [IDA, ISO]
- postsynaptic membrane [ISO]
- presynaptic active zone membrane [IDA]
- protein complex [IDA]
- terminal bouton [ISO]
- voltage-gated potassium channel complex [IBA, ISO]
Rattus norvegicus
Affinity Capture-MS
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.
Publication
Synaptic Protein Ubiquitination in Rat Brain Revealed by Antibody-based Ubiquitome Analysis.
Protein ubiquitination is an essential post-translational modification regulating neurodevelopment, synaptic plasticity, learning, and memory, and its dysregulation contributes to the pathogenesis of neurological diseases. Here we report a systematic analysis of ubiquitinated proteome (ubiquitome) in rat brain using a newly developed monoclonal antibody that recognizes the diglycine tag on lysine residues in trypsinized peptides (K-GG peptides). Initial antibody specificity analysis ... [more]
J. Proteome Res. Aug. 15, 2012; 0(0); [Pubmed: 22871113]
Throughput
- Low Throughput
Curated By
- BioGRID