BAIT
UBC
ubiquitin C
GO Process (2)
GO Function (2)
GO Component (2)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Rattus norvegicus
PREY
CDC42
cell division cycle 42
GO Process (59)
GO Function (9)
GO Component (22)
Gene Ontology Biological Process
- GTP catabolic process [TAS]
- Golgi organization [IMP]
- actin cytoskeleton organization [ISO]
- actin filament branching [IMP]
- actin filament bundle assembly [ISO]
- actin filament organization [IMP]
- adherens junction organization [ISO]
- canonical Wnt signaling pathway [ISO]
- cardiac conduction system development [ISO]
- cellular protein localization [ISO]
- dendritic cell migration [ISO]
- epidermis morphogenesis [ISO]
- epithelial cell-cell adhesion [ISO]
- epithelial-mesenchymal cell signaling [ISO]
- establishment of Golgi localization [IMP]
- establishment of cell polarity [TAS]
- establishment or maintenance of apical/basal cell polarity [ISO]
- filopodium assembly [ISO]
- hair follicle morphogenesis [ISO]
- hair follicle placode formation [ISO]
- heart contraction [ISO]
- keratinization [ISO]
- keratinocyte development [ISO]
- multicellular organism growth [ISO]
- negative regulation of gene expression [ISO]
- negative regulation of protein complex assembly [ISO]
- neuron fate determination [ISO]
- nuclear migration [ISO]
- nucleus localization [ISO]
- organelle transport along microtubule [IMP]
- positive regulation of DNA replication [IMP]
- positive regulation of JNK cascade [IDA]
- positive regulation of MAPK cascade [ISO]
- positive regulation of cytokinesis [ISO, ISS]
- positive regulation of gene expression [ISO]
- positive regulation of hair follicle cell proliferation [ISO]
- positive regulation of intracellular protein transport [IMP]
- positive regulation of metalloenzyme activity [IMP]
- positive regulation of neuron apoptotic process [IMP]
- positive regulation of peptidyl-serine phosphorylation [ISO]
- positive regulation of phosphatidylinositol 3-kinase activity [ISO]
- positive regulation of protein phosphorylation [ISO]
- positive regulation of pseudopodium assembly [ISO]
- positive regulation of substrate adhesion-dependent cell spreading [ISO, ISS]
- positive regulation of synapse structural plasticity [IMP]
- regulation of attachment of spindle microtubules to kinetochore [ISO, ISS]
- regulation of exocytosis [TAS]
- regulation of filopodium assembly [ISO, ISS]
- regulation of mitosis [ISO]
- regulation of protein catabolic process [ISO]
- regulation of protein heterodimerization activity [ISO]
- regulation of protein kinase activity [ISO]
- regulation of protein metabolic process [ISO]
- regulation of protein stability [ISO]
- response to glucose [TAS]
- single organismal cell-cell adhesion [ISO]
- sprouting angiogenesis [IMP]
- submandibular salivary gland formation [IEP]
- substantia nigra development [ISO]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
- Golgi membrane [IDA]
- apical part of cell [ISO]
- cell [ISO]
- cell periphery [ISO]
- cell projection [ISO]
- cell-cell junction [ISO]
- cytoplasm [ISO]
- cytoplasmic ribonucleoprotein granule [ISO]
- cytosol [TAS]
- extracellular vesicular exosome [ISO]
- filopodium [ISO]
- focal adhesion [ISO]
- leading edge membrane [ISO]
- membrane [ISO, ISS]
- midbody [ISO, ISS]
- mitotic spindle [ISO, ISS]
- myelin sheath [ISO]
- neuron projection [ISO]
- neuronal cell body [ISO]
- plasma membrane [IDA, ISO]
- secretory granule [IDA]
- spindle midzone [ISO, ISS]
Rattus norvegicus
Affinity Capture-MS
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.
Publication
Synaptic Protein Ubiquitination in Rat Brain Revealed by Antibody-based Ubiquitome Analysis.
Protein ubiquitination is an essential post-translational modification regulating neurodevelopment, synaptic plasticity, learning, and memory, and its dysregulation contributes to the pathogenesis of neurological diseases. Here we report a systematic analysis of ubiquitinated proteome (ubiquitome) in rat brain using a newly developed monoclonal antibody that recognizes the diglycine tag on lysine residues in trypsinized peptides (K-GG peptides). Initial antibody specificity analysis ... [more]
J. Proteome Res. Aug. 15, 2012; 0(0); [Pubmed: 22871113]
Throughput
- Low Throughput
Curated By
- BioGRID