BAIT
UBC
ubiquitin C
GO Process (2)
GO Function (2)
GO Component (2)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Rattus norvegicus
PREY
CXCL2
Mip-2, Scyb2
chemokine (C-X-C motif) ligand 2
GO Process (19)
GO Function (2)
GO Component (1)
Gene Ontology Biological Process
- G-protein coupled receptor signaling pathway [IBA]
- cellular response to interleukin-1 [IEP]
- cellular response to lipopolysaccharide [IEP]
- chemokine-mediated signaling pathway [IBA]
- immune response [IBA]
- inflammatory response [IBA]
- leukocyte chemotaxis [IMP]
- neuron death [IDA]
- neutrophil chemotaxis [IMP]
- positive regulation of cytosolic calcium ion concentration [IDA]
- positive regulation of leukocyte chemotaxis [IBA]
- regulation of cell proliferation [IBA]
- response to amphetamine [IEP]
- response to estradiol [IEP]
- response to gamma radiation [IEP]
- response to glucocorticoid [IEP]
- response to heat [IEP]
- response to molecule of bacterial origin [ISO]
- wound healing [IEP]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Rattus norvegicus
Affinity Capture-MS
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.
Publication
Synaptic Protein Ubiquitination in Rat Brain Revealed by Antibody-based Ubiquitome Analysis.
Protein ubiquitination is an essential post-translational modification regulating neurodevelopment, synaptic plasticity, learning, and memory, and its dysregulation contributes to the pathogenesis of neurological diseases. Here we report a systematic analysis of ubiquitinated proteome (ubiquitome) in rat brain using a newly developed monoclonal antibody that recognizes the diglycine tag on lysine residues in trypsinized peptides (K-GG peptides). Initial antibody specificity analysis ... [more]
J. Proteome Res. Aug. 15, 2012; 0(0); [Pubmed: 22871113]
Throughput
- Low Throughput
Curated By
- BioGRID